日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation.

从结构角度深入了解 RAS-PI3Kα 同工型特异性相互作用以及 RAS 在 PI3Kα 激活中的作用

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-55766-x
Czyzyk Daniel, Yan Wupeng, Messing Simon, Gillette William, Tsuji Takashi, Yamaguchi Mitsuhiro, Furuzono Shinji, Turner David M, Esposito Dominic, Nissley Dwight V, McCormick Frank, Simanshu Dhirendra K
RAS
发表日期：2025
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Prodrug nanotherapy demonstrates in vivo anticryptosporidial efficacy in a mouse model of chronic Cryptosporidium infection

前药纳米疗法在慢性隐孢子虫感染小鼠模型中显示出体内抗隐孢子虫疗效

期刊:
影响因子:
doi:10.1039/d4pm00093e
Ranjan, Amalendu P; Czyzyk, Daniel J; Martinez-Traverso, Griselle; Sadiqova, Aygul; Valhondo, Margarita; Schaefer, Deborah A; Spasov, Krasimir A; Jorgensen, William L; Vishwanatha, Jamboor K; Riggs, Michael W; Castellanos-Gonzalez, Alejandro; Anderson, Karen S
炎症/感染
发表日期：2024
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Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitors

以寄生性原生动物双功能人隐孢子虫TS-DHFR中的TS二聚体界面为靶点：虚拟筛选鉴定新型TS变构抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2020.127292
Ruiz, Victor G; Czyzyk, Daniel J; Kumar, Vidya P; Jorgensen, William L; Anderson, Karen S
发表日期：2020
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Understanding the structural basis of species selective, stereospecific inhibition for Cryptosporidium and human thymidylate synthase

了解隐孢子虫和人胸苷酸合成酶的物种选择性、立体特异性抑制的结构基础

期刊:FEBS Letters
影响因子:3
doi:10.1002/1873-3468.13474
Czyzyk, Daniel J; Valhondo, Margarita; Jorgensen, William L; Anderson, Karen S
发表日期：2019
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Novel allosteric covalent inhibitors of bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa identified by virtual screening

通过虚拟筛选鉴定出寄生性原生动物来源的新型双功能人隐孢子虫TS-DHFR变构共价抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2019.03.022
Ruiz, Victor; Czyzyk, Daniel J; Valhondo, Margarita; Jorgensen, William L; Anderson, Karen S
发表日期：2019
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Synthesis, kinetics and inhibition of Escherichia coli Heptosyltransferase I by monosaccharide analogues of Lipid A

脂质A单糖类似物对大肠杆菌庚糖基转移酶I的合成、动力学及抑制作用

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2018.01.040
Nkosana, Noreen K; Czyzyk, Daniel J; Siegel, Zarek S; Cote, Joy M; Taylor, Erika A
发表日期：2018
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A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium

纳米疗法策略显著增强了隐孢子虫双功能胸苷酸合成酶-二氢叶酸还原酶抑制剂的抗隐孢子虫活性。

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2015.03.091
Mukerjee, Anindita; Iyidogan, Pinar; Castellanos-Gonzalez, Alejandro; Cisneros, José A; Czyzyk, Daniel; Ranjan, Amalendu Prakash; Jorgensen, William L; White, A Clinton Jr; Vishwanatha, Jamboor K; Anderson, Karen S
发表日期：2015
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Lipopolysaccharide biosynthesis without the lipids: recognition promiscuity of Escherichia coli heptosyltransferase I

脂多糖生物合成无需脂质：大肠杆菌庚糖基转移酶 I 的识别混杂性

期刊:Biochemistry
影响因子:3
doi:10.1021/bi201581b
Czyzyk, Daniel J; Liu, Cassie; Taylor, Erika A
发表日期：2011
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