D'Haens Geert相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

The predictive value of intestinal ultrasound for treatment response in inflammatory bowel disease: a systematic review and pooled data analysis

肠道超声对炎症性肠病治疗反应的预测价值：系统评价和汇总数据分析

期刊:Journal of Crohns & Colitis

影响因子:8.7

doi:10.1093/ecco-jcc/jjag017

Vos, Johanna M B W; Teichert, Christoph; De Voogd, Floris A E; Pruijt, Maarten J; Jamaludin, Faridi S; D'Haens, Geert R A M; Benninga, Marc A; Koot, Bart G P; Gecse, Krisztina B

发表日期：2026

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Histopathological Findings of Appendix Specimens in Quiescent Ulcerative Colitis: Correlations With Clinical Outcomes in the ACCURE Trial

静止期溃疡性结肠炎阑尾标本的组织病理学发现：与 ACCURE 试验临床结果的相关性

期刊:United European Gastroenterology Journal

影响因子:6.7

doi:10.1002/ueg2.70177

Visser, Eva; Danielsson, Demy; Heuthorst, Lianne; D'Haens, Geert R; Bemelman, Willem A; Buskens, Christianne J; Mookhoek, Aart

发表日期：2026

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Selective SIK2/SIK3 inhibition reprograms pro- and antiinflammatory pathways in myeloid cells, improving autoimmune disease outcomes

选择性抑制SIK2/SIK3可重编程髓系细胞中的促炎和抗炎通路，从而改善自身免疫性疾病的预后。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.171776

De Vos, Steve; Desroy, Nicolas; Bellaire, Susan J; Fernandes, Anna Pereira; Lavazais, Stéphanie; Merciris, Didier; Delachaume, Carole; Robin-Jagerschmidt, Catherine; Cosson, Adrien; Lazaryan, Angela; Van Osselaer, Nancy; Amantini, David; Peixoto, Christophe; Colli, Maikel L; Van Eeckhoutte, Thomas; Hakonen, Tiina; Constant, Magali; Garcia-Hernandez, Alberto; Barron, Rahul; D'Haens, Geert; Böcher, Wulf O

自身免疫性疾病

免疫/内分泌

细胞生物学

发表日期：2026

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Etrasimod Treatment Modulates Circulating and Lymph Node-Derived Lymphocytes in Crohn's Disease

依曲莫德治疗可调节克罗恩病患者循环和淋巴结来源的淋巴细胞

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms27052447

Nikolakis, Dimitrios; Pruijt, Maarten J; Verhoeff, Jan; de Voogd, Floris A E; Teichert, Christoph; Ryan, Rathi D; Branquinho, Diogo; Crosby, Catherine; van de Sande, Marleen G H; Grootjans, Joep; D'Haens, Geert R

细胞生物学

发表日期：2026

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Colonic biopsy-associated microbial signatures are predictive of response to anti-TNFα biological therapy in Crohn's disease

结肠活检相关的微生物特征可预测克罗恩病患者对TNFα抑制剂生物疗法的反应

期刊:Frontiers in Cellular and Infection Microbiology

影响因子:4.8

doi:10.3389/fcimb.2026.1741002

Zafeiropoulou, Konstantina; Hageman, Ishtu L; Mu, Tianqi; Davids, Mark; Li Yim, Andrew Y F; Joustra, Vincent W; Hakvoort, Theodorus B M; Satsangi, Jack; Chronas, Konstantinos; Koelink, Pim J; Wildenberg, Manon E; van den Wijngaard, Rene M; D'Haens, Geert R; de Jonge, Wouter J

发表日期：2026

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Higher Vedolizumab Clearance Associates with Poor Therapeutic Outcomes during Intravenous Vedolizumab Maintenance Therapy in Crohn's Disease

克罗恩病患者接受静脉注射维多珠单抗维持治疗期间，较高的维多珠单抗清除率与较差的治疗效果相关。

期刊:Inflammatory Bowel Diseases

影响因子:4.3

doi:10.1093/ibd/izaf255

Anjie, Suzanne I; D'Haens, Geert R; Baert, Filip; Bossuyt, Peter; Hoentjen, Frank; Clasquin, Esmé; Molnár, Tamás; Löwenberg, Mark; Vermeire, Séverine; Panetta, J Carl; Dervieux, Thierry

发表日期：2026

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Mucosal B Cell Expansion and Maturation Contribute to Colitis Pathogenesis.

黏膜B细胞的扩增和成熟是结肠炎发病机制的促成因素。

期刊:Inflammatory Bowel Diseases

影响因子:4.3

doi:10.1093/ibd/izaf275

Fung Ivan C N, Koelink Pim J, Mulders Lieven G M, Admiraal Iris, Verseijden Caroline, Verhoeff Jan, Wildenberg Manon E, Luo Yi, D'Haens Geert R, Li Yim Andrew Y F, de Jonge Wouter J

细胞生物学

发表日期：2026

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One Subcutaneous 2-ml Injection of Mirikizumab is Bioequivalent to Two 1-ml Subcutaneous Injections in Healthy Participants

在健康受试者中，一次皮下注射2毫升Mirikizumab与两次皮下注射1毫升Mirikizumab具有生物等效性。

期刊:Advances in Therapy

doi:10.1007/s12325-025-03422-1

Otani, Yuki; Payne, Christopher D; Loftus, Edward V Jr; D'Haens, Geert; Ben Horin, Shomron; Upadhya K, Abhishek; Todd, Kristin; Pellanda, Paola; Shi, Galen; Zhang, Xin

发表日期：2026

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Utility of T2* and DWI-IVIM to distinguish inflammatory and noninflammatory strictures in Crohn's disease: a prospective cross-sectional cohort study

T2* 和 DWI-IVIM 在区分克罗恩病炎症性和非炎症性狭窄中的应用价值：一项前瞻性横断面队列研究

期刊:European Radiology Experimental

影响因子:3.6

doi:10.1186/s41747-026-00715-0

Beek, Kim Johanna; van Rijn, Kyra; de Voogd, Floris; Wassenaar, Nienke Petronella Maria; Buskens, Christianne; van der Bilt, Jarmila; Bemelman, Willem; D'Haens, Geert Renaat; Gecse, Krisztina Barbara; Horsthuis, Karin; Tielbeek, Jeroen; Mookhoek, Aart; Neefjes-Borst, Andra; Gurney-Champion, Oliver; Stoker, Jaap

发表日期：2026

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Efficacy and safety of ABBV-154 in patients with moderately to severely active Crohn's disease: a phase 2b, randomized, double-blind, placebo-controlled trial

ABBV-154治疗中重度活动性克罗恩病患者的疗效和安全性：一项2b期随机、双盲、安慰剂对照试验

期刊:Crohns Colitis 360

影响因子:2.6

doi:10.1093/crocol/otag014

Reinisch, Walter; Peyrin-Biroulet, Laurent; D'Haens, Geert; Sturm, Andreas; Anderson, Jaclyn K; Messina, Izabella; Arikan, Dilek; Zimmerman-Bennett, Alissa; Parmentier, Julie; Feng, Tian; D'Cunha, Ronilda; Lazar, Andreas; Louis, Edouard

发表日期：2026

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