日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chromophore charge-state switching through copper-dependent homodimerisation of an engineered green fluorescent protein

通过铜依赖的同源二聚化作用实现工程化绿色荧光蛋白的发色团电荷状态转换

Ahmed, Rochelle D; Vitsupakorn, Danoo; Hartwell, Kieran D; Albalawi, Karma; Rizkallah, Pierre J; Watson, Peter D; Jones, D Dafydd

Molecular dynamics guided identification of a brighter variant of superfolder Green Fluorescent Protein with increased photobleaching resistance

利用分子动力学方法鉴定出一种亮度更高的超折叠绿色荧光蛋白变体,该变体具有更强的光漂白抵抗能力。

Ahmed, Rochelle D; Jamieson, W David; Vitsupakorn, Danoo; Zitti, Athena; Pawson, Kai A; Castell, Oliver K; Watson, Peter D; Jones, D Dafydd

Structure, Function and Dynamics of mCoral, a pH-Responsive Engineered Variant of the mCherry Fluorescent Protein with Improved Hydrogen Peroxide Tolerance

mCoral的结构、功能和动力学:一种pH响应型mCherry荧光蛋白工程变体,具有更高的过氧化氢耐受性

Zitti, Athena; Aksakal, Ozan; Vitsupakorn, Danoo; Rizkallah, Pierre J; Mikolajek, Halina; Platts, James A; Menzies, Georgina E; Jones, D Dafydd

Optimising CNT-FET biosensor design through modelling of biomolecular electrostatic gating and its application to β-lactamase detection

通过生物分子静电门控建模优化 CNT-FET 生物传感器设计及其在 β-内酰胺酶检测中的应用

Rebecca E A Gwyther #, Sébastien Côté #, Chang-Seuk Lee #, Haosen Miao, Krithika Ramakrishnan, Matteo Palma, D Dafydd Jones

Glycosylation increases active site rigidity leading to improved enzyme stability and turnover

糖基化增加活性位点的刚性,从而提高酶的稳定性和周转率

Krithika Ramakrishnan, Rachel L Johnson, Samuel D Winter, Harley L Worthy, Christopher Thomas, Diana C Humer, Oliver Spadiut, Sarah H Hindson, Stephen Wells, Andrew H Barratt, Georgina E Menzies, Christopher R Pudney, D Dafydd Jones

A Proofreading Mutation with an Allosteric Effect Allows a Cluster of SARS-CoV-2 Viruses to Rapidly Evolve

一种具有变构效应的校对突变使得一群SARS-CoV-2病毒能够快速进化

Mack, Andrew H; Menzies, Georgina; Southgate, Alex; Jones, D Dafydd; Connor, Thomas R

Structure-Guided Engineering of a Family IV Cold-Adapted Esterase Expands Its Substrate Range

通过结构导向工程改造IV家族冷适应酯酶,扩大了其底物范围

Noby, Nehad; Johnson, Rachel L; Tyzack, Jonathan D; Embaby, Amira M; Saeed, Hesham; Hussein, Ahmed; Khattab, Sherine N; Rizkallah, Pierre J; Jones, D Dafydd

Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step

荧光蛋白Venus的生色团合成停滞揭示了最后氧化步骤的分子基础

Auhim, Husam Sabah; Grigorenko, Bella L; Harris, Tessa K; Aksakal, Ozan E; Polyakov, Igor V; Berry, Colin; Gomes, Gabriel Dos Passos; Alabugin, Igor V; Rizkallah, Pierre J; Nemukhin, Alexander V; Jones, D Dafydd

DNA-Directed Assembly of Carbon Nanotube-Protein Hybrids

DNA指导的碳纳米管-蛋白质杂合物组装

Freeley, Mark; Gwyther, Rebecca E A; Jones, D Dafydd; Palma, Matteo

Designed Artificial Protein Heterodimers With Coupled Functions Constructed Using Bio-Orthogonal Chemistry

利用生物正交化学构建具有耦合功能的人工蛋白质异二聚体

Johnson, Rachel L; Blaber, Hayley G; Evans, Tomas; Worthy, Harley L; Pope, Jacob R; Jones, D Dafydd