日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human-Monkey Chimeras for Modeling Human Disease: Opportunities and Challenges

利用人猴嵌合体构建人类疾病模型:机遇与挑战

De Los Angeles, Alejandro; Hyun, Insoo; Latham, Stephen R; Elsworth, John D; Redmond, D Eugene Jr

Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates

α-突触核蛋白功能丧失是帕金森病病理的促成因素吗?来自非人灵长类动物的证据

Collier, Timothy J; Redmond, D Eugene Jr; Steece-Collier, Kathy; Lipton, Jack W; Manfredsson, Fredric P

Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target

在多巴胺耗竭的猴子中脑中,人类神经干细胞在GDNF过表达后能够长期存活,并向合适的靶点投射神经突。

Wakeman, Dustin R; Redmond, D Eugene Jr; Dodiya, Hemraj B; Sladek, John R Jr; Leranth, Csaba; Teng, Yang D; Samulski, R Jude; Snyder, Evan Y

Primate phencyclidine model of schizophrenia: sex-specific effects on cognition, brain derived neurotrophic factor, spine synapses, and dopamine turnover in prefrontal cortex

苯环利定灵长类精神分裂症模型:对认知、脑源性神经营养因子、脊突触和前额皮质多巴胺周转的性别特异性影响

Elsworth, John D; Groman, Stephanie M; Jentsch, James D; Leranth, Csaba; Redmond, D Eugene Jr; Kim, Jung D; Diano, Sabrina; Roth, Robert H

Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates

产前接触双酚A会影响非人灵长类动物的中脑多巴胺神经元和海马棘突触。

Elsworth, John D; Jentsch, J David; Vandevoort, Catherine A; Roth, Robert H; Redmond, D Eugene Jr; Leranth, Csaba

Loss of asymmetric spine synapses in prefrontal cortex of motor-asymptomatic, dopamine-depleted, cognitively impaired MPTP-treated monkeys

MPTP处理的无运动症状、多巴胺耗竭、认知障碍的猴子前额皮质中不对称棘突突触的丢失

Elsworth, John D; Leranth, Csaba; Redmond, D Eugene Jr; Roth, Robert H

Comparison of fresh to fixed weights of the vervet monkey (Chlorocebus sabaeus) placenta and its relation to gestational age

比较绿猴(Chlorocebus sabaeus)胎盘的新鲜重量和固定重量及其与妊娠期的关系

DeMartelly, Victoria; Hurley, Patrick; Lawrence, Mathew; Redmond, D Eugene Jr; Rutherford, Julienne

Functional multipotency of stem cells: a conceptual review of neurotrophic factor-based evidence and its role in translational research

干细胞的功能性多能性:基于神经营养因子的证据及其在转化研究中的作用的概念性综述

Teng, Yang D; Yu, Dou; Ropper, Alexander E; Li, Jianxue; Kabatas, Serdar; Wakeman, Dustin R; Wang, Junmei; Sullivan, Maryrose P; Redmond, D Eugene Jr; Langer, Robert; Snyder, Evan Y; Sidman, Richard L

Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles

重组AAV基因组的工程改造与筛选:一种生产靶向生物纳米颗粒的新策略

Li, Wuping; Asokan, Aravind; Wu, Zhijian; Van Dyke, Terry; DiPrimio, Nina; Johnson, Jarrod S; Govindaswamy, Lakshmanan; Agbandje-McKenna, Mavis; Leichtle, Stefan; Redmond, D Eugene Jr; McCown, Thomas J; Petermann, Kimberly B; Sharpless, Norman E; Samulski, Richard J

Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease

在帕金森病灵长类动物模型中,人类神经干细胞沿黑质纹状体通路迁移

Bjugstad, Kimberly B; Teng, Yang D; Redmond, D Eugene Jr; Elsworth, John D; Roth, Robert H; Cornelius, Shannon K; Snyder, Evan Y; Sladek, John R Jr