日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of a tetrahydroindazolone-based HDAC6 inhibitor with in-vivo anti-arthritic activity

开发具有体内抗关节炎活性的四氢吲哚基 HDAC6 抑制剂

Hyun-Mo Yang, Changsik Lee, Jaeki Min, Nina Ha, Daekwon Bae, Gibeom Nam, Hyun-Ju Park

Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis

抑制组蛋白去乙酰化酶 6 可抑制炎症性关节炎中的炎症反应和成纤维细胞样滑膜细胞的侵袭性

Jin Kyun Park, Sehui Shon, Hyun Jung Yoo, Dong-Hyeon Suh, Daekwon Bae, Jieun Shin, Jae Hyun Jun, Nina Ha, Hyeseung Song, Young Il Choi, Thomas Pap, Yeong Wook Song

CKD-506: A novel HDAC6-selective inhibitor that exerts therapeutic effects in a rodent model of multiple sclerosis

CKD-506:一种新型 HDAC6 选择性抑制剂,在多发性硬化症啮齿动物模型中发挥治疗作用

Daekwon Bae, Ji-Young Lee, Nina Ha, Jinsol Park, Jiyeon Baek, Donghyeon Suh, Hee Seon Lim, Soo Min Ko, Taehee Kim, Da Som Jeong, Woo-Chan Son

Therapeutic potential of CKD-506, a novel selective histone deacetylase 6 inhibitor, in a murine model of rheumatoid arthritis

CKD-506(一种新型选择性组蛋白去乙酰化酶 6 抑制剂)在小鼠类风湿性关节炎模型中的治疗潜力

Jin Kyun Park, Yu Jin Jang, Bo Ram Oh, Jieun Shin, Daekwon Bae, Nina Ha, Young Il Choi, Gi Soo Youn, Jinseu Park, Eun Young Lee, Eun Bong Lee, Yeong Wook Song

Therapeutic effect of a novel histone deacetylase 6 inhibitor, CKD-L, on collagen-induced arthritis in vivo and regulatory T cells in rheumatoid arthritis in vitro

新型组蛋白去乙酰化酶 6 抑制剂 CKD-L 对胶原诱导性关节炎的体内治疗作用和对类风湿关节炎调节性 T 细胞的体外治疗作用

Bo Ram Oh, Dong-Hyeon Suh, Daekwon Bae, Nina Ha, Young Il Choi, Hyun Jung Yoo, Jin Kyun Park, Eun Young Lee, Eun Bong Lee, Yeong Wook Song