Dahea相关文献与解析，生知库 | 链接生命科学的每一步

Dahea Lee #, Dongsu Kim #, Donggeon Kim #, Jisu Kang, Kiram Lee, Hyunji Lee, Yujin Yoon, Youngin Lee, Nahmju Kim, Byoung Chul Cho, Jihoon Chang, Byoung Chul Lee

肿瘤

发表日期：2025

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In vitro human ion channel assays predictive of drug-induced seizure

体外人离子通道检测预测药物诱发癫痫

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfae148

Cohen, Jennifer D; You, Dahea; Sharma, Ashok K; Takai, Takafumi; Hara, Hideto; Sales, Vicencia T; Yukawa, Tomoya; Cai, Beibei

Nonalcoholic steatohepatitis increases plasma retention of sorafenib-glucuronide in a mouse model by altering hepatocyte hopping

非酒精性脂肪性肝炎通过改变肝细胞跳跃，增加小鼠模型中索拉非尼葡糖苷酸的血浆滞留。

期刊:Acta Pharmaceutica Sinica B

影响因子:14.6

doi:10.1016/j.apsb.2024.09.004

Toth, Erica; Li, Hui; Frost, Kayla; Sample, Paxton; Jilek, Joseph; Greenfield, Siennah; You, Dahea; Kozlosky, Danielle; Goedken, Michael; Paine, Mary F; Aleksunes, Lauren; Cherrington, Nathan

Acute contact with profibrotic macrophages mechanically activates fibroblasts via αvβ3 integrin-mediated engagement of Piezo1

与促纤维化巨噬细胞的急性接触可通过αvβ3整合素介导的Piezo1结合，机械性地激活成纤维细胞。

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.adp4726

Maya Ezzo ，Katrin Spindler ，Jun Bo Wang ，Dahea Lee ，Gilbert Pecoraro ，Justin Cowen ，Pardis Pakshir ，Boris Hinz

Therapeutic effiacy of T cells expressing chimeric antigen receptor derived from a mesothelin-specific scFv in orthotopic human pancreatic cancer animal models.

表达源自间皮素特异性 scFv 的嵌合抗原受体的 T 细胞在原位人胰腺癌动物模型中的治疗效果

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2021.12.005

Lee Hyeon Ho, Kim Irene, Kim Un Kyo, Choi Suk San, Kim Tae Yang, Lee Dahea, Lee Youngeun, Lee Jaehee, Jo Jinhui, Lee Young-Tae, Lee Ho Jeong, Kim Sun Jin, Ahn Jong Seong

Profiling Secreted miRNA Biomarkers of Chemical-Induced Neurodegeneration in Human iPSC-Derived Neurons

分析人诱导多能干细胞来源神经元中化学诱导神经退行性变的分泌型miRNA生物标志物

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfac011

You, Dahea; Cohen, Jennifer D; Pustovalova, Olga; Lewis, Lauren; Shen, Lei

Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice

亚硝化应激和脂质稳态是齐留通在遗传敏感小鼠中引起肝毒性和耐药性的机制

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfaa037

You, Dahea; Lyn-Cook, Lascelles E; Gatti, Daniel M; Bell, Natalie; Mayeux, Philip R; James, Laura P; Mattes, William B; Larson, Gary J; Harrill, Alison H

毒理研究

发表日期：2020

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Increased MDR1 Transporter Expression in Human Brain Endothelial Cells Through Enhanced Histone Acetylation and Activation of Aryl Hydrocarbon Receptor Signaling

通过增强组蛋白乙酰化和激活芳烃受体信号传导增加人脑内皮细胞中的 MDR1 转运蛋白表达

期刊:Molecular Neurobiology

影响因子:4.6

doi:10.1007/s12035-019-1565-7

Dahea You, Xia Wen, Ludwik Gorczyca, Ayeshia Morris, Jason R Richardson, Lauren M Aleksunes

Brain region-specific regulation of histone acetylation and efflux transporters in mice

小鼠脑区域特异性调节组蛋白乙酰化和外排转运体

期刊:Journal of Biochemical and Molecular Toxicology

影响因子:3.2

doi:10.1002/jbt.22318

Dahea You, Hye Min Shin, Fatimah Mosaad, Jason R Richardson, Lauren M Aleksunes

表观遗传

发表日期：2019

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Xenobiotic transporters and kidney injury

异生物质转运体与肾损伤

期刊:Advanced Drug Delivery Reviews

影响因子:17.6

doi:10.1016/j.addr.2017.01.005

George, Blessy; You, Dahea; Joy, Melanie S; Aleksunes, Lauren M

Harnessing the Potential of FAP-IL12mut TMEkine for Targeted and Enhanced Antitumor Responses

利用 FAP-IL12mut TMEkine 的潜力实现针对性和增强的抗肿瘤反应

In vitro human ion channel assays predictive of drug-induced seizure

体外人离子通道检测预测药物诱发癫痫

Nonalcoholic steatohepatitis increases plasma retention of sorafenib-glucuronide in a mouse model by altering hepatocyte hopping

非酒精性脂肪性肝炎通过改变肝细胞跳跃，增加小鼠模型中索拉非尼葡糖苷酸的血浆滞留。

Acute contact with profibrotic macrophages mechanically activates fibroblasts via αvβ3 integrin-mediated engagement of Piezo1

与促纤维化巨噬细胞的急性接触可通过αvβ3整合素介导的Piezo1结合，机械性地激活成纤维细胞。

Therapeutic effiacy of T cells expressing chimeric antigen receptor derived from a mesothelin-specific scFv in orthotopic human pancreatic cancer animal models.

表达源自间皮素特异性 scFv 的嵌合抗原受体的 T 细胞在原位人胰腺癌动物模型中的治疗效果

Profiling Secreted miRNA Biomarkers of Chemical-Induced Neurodegeneration in Human iPSC-Derived Neurons

分析人诱导多能干细胞来源神经元中化学诱导神经退行性变的分泌型miRNA生物标志物

Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice

亚硝化应激和脂质稳态是齐留通在遗传敏感小鼠中引起肝毒性和耐药性的机制

Increased MDR1 Transporter Expression in Human Brain Endothelial Cells Through Enhanced Histone Acetylation and Activation of Aryl Hydrocarbon Receptor Signaling

通过增强组蛋白乙酰化和激活芳烃受体信号传导增加人脑内皮细胞中的 MDR1 转运蛋白表达

Brain region-specific regulation of histone acetylation and efflux transporters in mice

小鼠脑区域特异性调节组蛋白乙酰化和外排转运体

Xenobiotic transporters and kidney injury

异生物质转运体与肾损伤