Designing 5' UTR sequences improves the capacity of mRNA therapeutics in preclinical models of aging and obesity.
设计 5' UTR 序列可以提高 mRNA 疗法在衰老和肥胖的临床前模型中的疗效。
期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.12.060
Yoon Subin, Cho Hyeonggon, Lee Jisun, Ha Sunghyun, Lee Suyeon, Lee Yu-Sun, Cho Youngran, Ha Dahyeon, Oh Ayoung, Lee Seonghyun, Jeong Dahee, Cho Jun, Park Sang-In, Nam Jae-Hwan, Lee Young-Suk