Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein.
应用药代动力学/药效学模型连接小鼠抗肿瘤疗效和猴子毒理学数据，以确定白细胞介素-10 Fc融合蛋白的治疗指数
期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2022.829063
Yang Zheng, Loy James, Poirson Brian, Dai Yanshan, Rajendran Surendran, Xu Shihua, Spires Vanessa, Gururajan Murali, Lin Zheng, Arbanas Jaren, Carl Stephen, Pace Samantha, Wang Yun, Mehl John, Vasudevan Krishna, Spires Thomas, Novosiadly Ruslan, Coker Shodeinde, Perez Raymond, Covello Kelly, Morin Paul, Graziano Robert, Broz Miranda, Lehman-McKeeman Lois
