日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models

研究抗寄生虫药物吡喹酮在体外和体内临床前模型中的抗纤维化作用

Justin Komguep Nono, Kai Fu, Thabo Mpotje, Georgianna Varrone, Nada Abdel Aziz, Paballo Mosala, Lerato Hlaka, Severin Donald Kamdem, Daigen Xu, Thomas Spangenberg, Frank Brombacher

Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

使用新型口服生物可利用小分子抑制剂 RO9021 选择性抑制脾脏酪氨酸激酶 (SYK),影响各种先天性和适应性免疫反应:对 SYK 抑制剂在自身免疫性疾病治疗中的意义

Cheng Liao, Jonathan Hsu, Yong Kim, Dong-Qing Hu, Daigen Xu, Jun Zhang, Achal Pashine, John Menke, Toni Whittard, Natasha Romero, Theresa Truitt, Michelle Slade, Christine Lukacs, Johannes Hermann, Mingyan Zhou, Matthew Lucas, Satwant Narula, Julie DeMartino, Seng-Lai Tan

A fluorogenic near-infrared imaging agent for quantifying plasma and local tissue renin activity in vivo and ex vivo

用于体内和体外量化血浆和局部组织肾素活性的荧光近红外成像剂

Jun Zhang, Dorin V Preda, Kristine O Vasquez, Jeff Morin, Jeannine Delaney, Bagna Bao, M David Percival, Daigen Xu, Dan McKay, Michael Klimas, Bohumil Bednar, Cyrille Sur, David Z Gao, Karen Madden, Wael Yared, Milind Rajopadhye, Jeffrey D Peterson

Prostacyclin antagonism reduces pain and inflammation in rodent models of hyperalgesia and chronic arthritis

前列环素拮抗剂可减轻痛觉过敏和慢性关节炎啮齿动物模型中的疼痛和炎症

Anne-Marie Pulichino, Steve Rowland, Tom Wu, Patsy Clark, Daigen Xu, Marie-Claude Mathieu, Denis Riendeau, Laurent P Audoly