日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Disruption of perinatal myeloid niches impacts the aging clock of pancreatic β cells

围产期髓系微环境的破坏会影响胰岛β细胞的衰老时钟。

Jessica O'Sell ,Vincenzo Cirulli ,Stephanie Pardike ,Marie Aare-Bentsen ,Patima Sdek ,Jasmine Anderson ,Dale W Hailey ,Mary C Regier ,Sina A Gharib ,Laura Crisa

Advancements in high-resolution 3D microscopy analysis of endosomal morphology in postmortem Alzheimer's disease brains

阿尔茨海默病患者死后大脑内体形态的高分辨率 3D 显微镜分析进展

Shannon E Rose, C Andrew Williams, Dale W Hailey, Swati Mishra, Amanda Kirkland, C Dirk Keene, Gwenn A Garden, Suman Jayadev, Jessica E Young

The Alzheimer's gene SORL1 is a regulator of endosomal traffic and recycling in human neurons

阿尔茨海默氏症基因 SORL1 是人类神经元内体运输和循环的调节器

Swati Mishra #, Allison Knupp #, Marcell P Szabo, Charles A Williams, Chizuru Kinoshita, Dale W Hailey, Yuliang Wang, Olav M Andersen, Jessica E Young

Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing

AD风险基因SORL1的缺失选择性地损害神经元内体运输,且该过程独立于淀粉样蛋白生成APP加工。

Allison Knupp,Swati Mishra,Refugio Martinez,Jacquelyn E Braggin,Marcell Szabo,Chizuru Kinoshita,Dale W Hailey,Scott A Small,Suman Jayadev,Jessica E Young

Cumulative mitochondrial activity correlates with ototoxin susceptibility in zebrafish mechanosensory hair cells

斑马鱼机械感觉毛细胞中累积线粒体活性与耳毒素敏感性相关

Sarah B Pickett, Eric D Thomas, Joy Y Sebe, Tor Linbo, Robert Esterberg, Dale W Hailey, David W Raible

Functional mechanotransduction is required for cisplatin-induced hair cell death in the zebrafish lateral line

顺铂诱导斑马鱼侧线毛细胞死亡需要功能性机械转导

Andrew J Thomas, Dale W Hailey, Tamara M Stawicki, Patricia Wu, Allison B Coffin, Edwin W Rubel, David W Raible, Julian A Simon, Henry C Ou

Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone

Slc4a1b 氯化物/碳酸氢盐交换器功能的丧失可保护斑马鱼突变体珀耳塞福涅的机械感觉毛细胞免受氨基糖苷类药物的损伤

Dale W Hailey, Brock Roberts, Kelly N Owens, Andrew K Stewart, Tor Linbo, Remy Pujol, Seth L Alper, Edwin W Rubel, David W Raible