日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bnip3lb-driven mitophagy maintains fate of the embryonic hematopoietic stem cell pool

Bnip3lb驱动的线粒体自噬维持胚胎造血干细胞库的命运

Meader, Eleanor; Walcheck, Morgan T; Leder, Mindy R; Delaney, Patrice; Falchetti, Marcelo; Jing, Ran; Li, Christopher; Kambli, Netra K; Wrighton, Paul J; Sugden, Wade W; Najia, Mohamad A; Oderberg, Isaac M; Taylor, Vivian M; LeBlanc, Zachary C; Quenzer, Eleanor D; Lim, Sung-Eun; Schlaeger, Thorsten; Daley, George Q; Goessling, Wolfram; North, Trista E

Soluble Notch agonist enables human ameloblast maturation and enamel-like tissue formation for tooth regeneration.

可溶性 Notch 激动剂能够促进人类成釉细胞成熟和形成类似牙釉质的组织,从而实现牙齿再生。

Patni Anjali P, Mout Rubul, Alghadeer Ammar, Moore Rachel H, Nademi Samera, Ausk Brandon J, Huber Philippe, Keshri Riya, Regier Mary, Cornell Robert A, Gross Ted, Freedman Benjamin S, Daley George Q, Baker David, Mathieu Julie, Ruohola-Baker Hannele

David Baltimore: Scientist, leader, and mentor

大卫·巴尔的摩:科学家、领导者和导师

Andrews, Nancy C; Daley, George Q

A novel hyperactive BCR::ABL1 ( e6a3 ) variant confers resistance to combined asciminib plus ponatinib therapy

一种新型高活性 BCR::ABL1 (e6a3) 变体赋予了对阿西米尼联合帕纳替尼治疗的耐药性

Malekzadeh, Malakeh; Ghimire, Hemendra; Popuri, Karteek; Fujita, Kazuki; Salhotra, Amandeep; Yamauchi, Dave; Chen, Bihong; Froelich, Jerry; Storme, Guy; Stein, Anthony; Beg, Mirza Faisal; Wong, Jeffrey; Malki, Monzr M Al; Hui, Susanta K; Nardi, Valentina; Schwieterman, Joshua; Ansari, Sekhu; Kincaid, Zachary; Azhar, Mohammad; Yousuf, Tahira; Amir, Noor; Khan, Areeba; Kesarwani, Meenu; Ryall, Scott; Brunner, Andrew M; Capilla Guerra, Maria Reyes; Griffin, Gabriel K; Nassar, Nicolas; Daley, George Q; Azam, Mohammad

Efficient Generation of Functional TCRαβ(+) Cytotoxic T Cells from hiPSCs via Small-Molecule Modulation

通过小分子调控从hiPSCs高效生成功能性TCRαβ(+)细胞毒性T细胞

Kubaczka, Caroline; Kambli, Netra; Windisch, Roland; Yu, Kelly; Zhao, Yunliang; Wu, Sharon; Frenis, Katie; Walcheck, Morgan T; Falchetti, Marcelo; Najia, Mohamad; LeBlanc, Zachary C; North, Trista E; Rowe, R Grant; Daley, George Q; Schlaeger, Thorsten M

Maturation and persistence of CAR T cells derived from human pluripotent stem cells via chemical inhibition of G9a/GLP

通过化学抑制G9a/GLP促进人多能干细胞来源的CAR T细胞的成熟和持久性

Jing, Ran; Falchetti, Marcelo; Han, Tianxiao; Najia, Mohamad; Hensch, Luca T; Meader, Eleanor; Lummertz da Rocha, Edroaldo; Kononov, Martin; Wang, Stephanie; Bingham, Trevor; Li, Zhiheng; Zhao, Yunliang; Frenis, Katie; Kubaczka, Caroline; Yang, Song; Jha, Deepak; Rodrigues-Luiz, Gabriela F; Rowe, R Grant; Schlaeger, Thorsten M; Maus, Marcela V; North, Trista E; Zon, Leonard I; Daley, George Q

EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity

EZH1抑制可产生具有增强抗肿瘤活性的成熟iPSC衍生CAR T细胞

Jing, Ran; Scarfo, Irene; Najia, Mohamad Ali; Lummertz da Rocha, Edroaldo; Han, Areum; Sanborn, Michael; Bingham, Trevor; Kubaczka, Caroline; Jha, Deepak K; Falchetti, Marcelo; Schlaeger, Thorsten M; North, Trista E; Maus, Marcela V; Daley, George Q

Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors

通过谱系限制性前体细胞的重新指定,从人类多能干细胞诱导多能造血祖细胞

Doulatov, Sergei; Vo, Linda T; Chou, Stephanie S; Kim, Peter G; Arora, Natasha; Li, Hu; Hadland, Brandon K; Bernstein, Irwin D; Collins, James J; Zon, Leonard I; Daley, George Q

SF3B1K700E mutation in human embryonic stem cells causes aberrant expression of immune-related genes

人类胚胎干细胞中的SF3B1K700E突变导致免疫相关基因的异常表达

Dastpak, Mahtab; Mimoso, Claudia A; Farshchian, Moein; Paraggio, Christina L; Leonard, Claudia E; Yin, Shanye; Chi, Binkai; Nassar, Kelsey W; Rowe, R Grant; Zhang, Jiuchun; Hou, Zhonggang; Daley, George Q; Adelman, Karen; Reed, Robin

A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs

一种不含异种成分的红细胞分化配方,利用体细胞来源的患者诱导多能干细胞(iPSCs)模拟镰状细胞病。

Conway, Ashlee J; Rosanwo, Tolulope O; Williamson, Thomas E; Landry, Samuel; Kinney, Melissa A; Clark, Martha A; Vo, Linda T; Rowe, R Grant; Marion, William; Zhang, Yosra; Mullin, Nathaniel K; Shi, Michael; Archer, Natasha M; Heeney, Matthew M; Schlaeger, Thorsten M; Bauer, Daniel E; Duraisingh, Manoj T; Brugnara, Carlo; North, Trista E; Daley, George Q