日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Positional scanning and computational modeling reveal determinants of legumain transpeptidase activity

位置扫描和计算建模揭示了legumain转肽酶活性的决定因素

Klaushofer, Rupert; Dahms, Sven O; Brandstetter, Hans; Dall, Elfriede

Protocol for producing brain-derived neurotrophic factor and neurotrophin-4 in their pro and active form in Escherichia coli.

在大肠杆菌中生产脑源性神经营养因子和神经营养因子-4的前体和活性形式的方案

Holzner Christoph, Böttinger Katharina, Huber Christian G, Dall Elfriede, Brandstetter Hans

Protocol for the recombinant expression and purification of the LSAM domain of human legumain in E. coli.

大肠杆菌中人legumain LSAM结构域重组表达和纯化方案

Dahms Sven O, Wieland Alexander C, Brandstetter Hans, Dall Elfriede

The Peptide Ligase Activity of Human Legumain Depends on Fold Stabilization and Balanced Substrate Affinities

人源Legumain的肽连接酶活性取决于折叠稳定性和平衡的底物亲和力

Dall, Elfriede; Stanojlovic, Vesna; Demir, Fatih; Briza, Peter; Dahms, Sven O; Huesgen, Pitter F; Cabrele, Chiara; Brandstetter, Hans

Laser-facilitated epicutaneous immunotherapy with hypoallergenic beta-glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of allergic asthma.

在过敏性哮喘小鼠模型中,采用低过敏性β-葡聚糖新糖缀合物进行激光辅助经皮免疫疗法可抑制肺部炎症并避免局部副作用

Korotchenko Evgeniia, Schießl Viktoria, Scheiblhofer Sandra, Schubert Mario, Dall Elfriede, Joubert Isabella A, Strandt Helen, Neuper Theresa, Sarajlic Muamera, Bauer Renate, Geppert Mark, Joedicke David, Wildner Sabrina, Schaller Susanne, Winkler Stephan, Gadermaier Gabriele, Horejs-Hoeck Jutta, Weiss Richard

Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design

克鲁扎因结构:脱辅基克鲁扎因和与S-甲基硫代甲磺酸酯结合的克鲁扎因及其对药物设计的影响

Barbosa da Silva, Elany; Dall, Elfriede; Briza, Peter; Brandstetter, Hans; Ferreira, Rafaela Salgado

Distinct Roles of Catalytic Cysteine and Histidine in the Protease and Ligase Mechanisms of Human Legumain As Revealed by DFT-Based QM/MM Simulations

基于DFT的QM/MM模拟揭示了人Legumain蛋白酶和连接酶机制中催化半胱氨酸和组氨酸的不同作用

Elsässer, Brigitta; Zauner, Florian B; Messner, Johann; Soh, Wai Tuck; Dall, Elfriede; Brandstetter, Hans

Structure and mechanism of an aspartimide-dependent peptide ligase in human legumain

人legumain中天冬酰亚胺依赖性肽连接酶的结构和机制

Dall, Elfriede; Fegg, Julia C; Briza, Peter; Brandstetter, Hans

Protease recognition sites in Bet v 1a are cryptic, explaining its slow processing relevant to its allergenicity

Bet v 1a 中的蛋白酶识别位点较为隐蔽,这解释了其缓慢的加工过程及其致敏性。

Freier, Regina; Dall, Elfriede; Brandstetter, Hans

Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation

对半乳糖蛋白酶的机制和结构研究解释了其酶原性、独特的激活途径和调控机制。

Dall, Elfriede; Brandstetter, Hans