日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Adaptation of Aglycosylated Monoclonal Antibodies for Improved Production in Komagataella phaffii

利用非糖基化单克隆抗体提高柯马加塔氏菌(Komagataella phaffii)的产量

Yang, Yuchen; Dalvie, Neil C; Brady, Joseph R; Naranjo, Christopher A; Lorgeree, Timothy; Rodriguez-Aponte, Sergio A; Johnston, Ryan S; Tracey, Mary K; Elenberger, Carmen M; Lee, Eric; Tié, Mark; Love, Kerry R; Love, J Christopher

Microbial Catalysis for CO(2) Sequestration: A Geobiological Approach

微生物催化二氧化碳封存:一种地质生物学方法

Van Den Berghe, Martin; Walworth, Nathan G; Dalvie, Neil C; Dupont, Chris L; Springer, Michael; Andrews, M Grace; Romaniello, Stephen J; Hutchins, David A; Montserrat, Francesc; Silver, Pamela A; Nealson, Kenneth H

CRISPR-Cas9 knockout screen informs efficient reduction of the Komagataella phaffii secretome

CRISPR-Cas9基因敲除筛选揭示了有效减少Komagataella phaffii分泌组的方法

Dalvie, Neil C; Lorgeree, Timothy R; Yang, Yuchen; Rodriguez-Aponte, Sergio A; Whittaker, Charles A; Hinckley, Joshua A; Clark, John J; Del Rosario, Amanda M; Love, Kerry R; Love, J Christopher

Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants.

对刺突蛋白 RBD 中隐蔽表位进行分子工程改造,可提高其生产性能和对 SARS-CoV-2 变种的中和广度

Rodriguez-Aponte Sergio A, Dalvie Neil C, Wong Ting Y, Johnston Ryan S, Naranjo Christopher A, Bajoria Sakshi, Kumru Ozan S, Kaur Kawaljit, Russ Brynnan P, Lee Katherine S, Cyphert Holly A, Barbier Mariette, Rao Harish D, Rajurkar Meghraj P, Lothe Rakesh R, Shaligram Umesh S, Batwal Saurabh, Chandrasekaran Rahul, Nagar Gaurav, Kleanthous Harry, Biswas Sumi, Bevere Justin R, Joshi Sangeeta B, Volkin David B, Damron F Heath, Love J Christopher

Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity

鼻内接种脂质体偶联免疫原可促进抗原经黏膜吸收,从而增强黏膜和全身免疫力。

Hartwell, Brittany L; Melo, Mariane B; Xiao, Peng; Lemnios, Ashley A; Li, Na; Chang, Jason Y H; Yu, Jingyou; Gebre, Makda S; Chang, Aiquan; Maiorino, Laura; Carter, Crystal; Moyer, Tyson J; Dalvie, Neil C; Rodriguez-Aponte, Sergio A; Rodrigues, Kristen A; Silva, Murillo; Suh, Heikyung; Adams, Josetta; Fontenot, Jane; Love, J Christopher; Barouch, Dan H; Villinger, Francois; Ruprecht, Ruth M; Irvine, Darrell J

Simplified Gene Knockout by CRISPR-Cas9-Induced Homologous Recombination

利用 CRISPR-Cas9 诱导的同源重组进行简化的基因敲除

Dalvie, Neil C; Lorgeree, Timothy; Biedermann, Andrew M; Love, Kerry R; Love, J Christopher

Host-Informed Expression of CRISPR Guide RNA for Genomic Engineering in Komagataella phaffii

利用宿主信息调控CRISPR向导RNA表达进行Komagataella phaffii基因组工程

Dalvie, Neil C; Leal, Justin; Whittaker, Charles A; Yang, Yuchen; Brady, Joseph R; Love, Kerry R; Love, J Christopher

Identifying Improved Sites for Heterologous Gene Integration Using ATAC-seq

利用ATAC-seq技术鉴定异源基因整合的更优位点

Brady, Joseph R; Tan, Melody C; Whittaker, Charles A; Colant, Noelle A; Dalvie, Neil C; Love, Kerry Routenberg; Love, J Christopher