日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy

隐孢子虫赖氨酰tRNA合成酶抑制剂阐明了溶解度和渗透性之间的相互作用,而这种相互作用是实现疗效所必需的。

Caldwell, Nicola; Peet, Caroline; Miller, Peter; Colon, Beatrice L; Taylor, Malcolm G; Cocco, Mattia; Dawson, Alice; Lukac, Iva; Teixeira, Jose E; Robinson, Lee; Frame, Laura; Seizova, Simona; Damerow, Sebastian; Tamaki, Fabio; Post, John; Riley, Jennifer; Mutter, Nicole; Hanna, Jack C; Ferguson, Liam; Hu, Xiao; Tinti, Michele; Forte, Barbara; Norcross, Neil R; Campbell, Peter S; Svensen, Nina; Caldwell, Flora C; Jansen, Chimed; Postis, Vincent; Read, Kevin D; Huston, Christopher D; Gilbert, Ian H; Baragaña, Beatriz; Pawlowic, Mattie C

A broadly active fucosyltransferase LmjFUT1 whose mitochondrial localization and activity are essential in parasitic Leishmania

LmjFUT1是一种具有广泛活性的岩藻糖基转移酶,其线粒体定位和活性对寄生利什曼原虫至关重要。

Guo, Hongjie; Damerow, Sebastian; Penha, Luciana; Menzies, Stefanie; Polanco, Gloria; Zegzouti, Hicham; Ferguson, Michael A J; Beverley, Stephen M

An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei.

锥虫线粒体中存在一种必需的、动质体特异性的 GDP-Fuc: β-D-Gal α-1,2-岩藻糖基转移酶

Bandini Giulia, Damerow Sebastian, Sempaio Guther Maria Lucia, Guo Hongjie, Mehlert Angela, Paredes Franco Jose Carlos, Beverley Stephen, Ferguson Michael Aj

Correction: Depletion of UDP-Glucose and UDP-Galactose Using a Degron System Leads to Growth Cessation of Leishmania major

更正:利用降解系统消耗UDP-葡萄糖和UDP-半乳糖会导致利什曼原虫生长停止。

Damerow, Sebastian; Hoppe, Carolin; Bandini, Giulia; Zarnovican, Patricia; Buettner, Falk F R; Lüder, Carsten G K; Ferguson, Michael A J; Routier, Françoise H

Depletion of UDP-Glucose and UDP-Galactose Using a Degron System Leads to Growth Cessation of Leishmania major

利用降解系统消耗UDP-葡萄糖和UDP-半乳糖会导致利什曼原虫生长停止。

Damerow, Sebastian; Hoppe, Carolin; Bandini, Giulia; Zarnovican, Patricia; Buettner, Falk F R; Lüder, Carsten G K; Ferguson, Michael A J; Routier, Françoise H

Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis.

利什曼原虫UDP-糖焦磷酸化酶回收半乳糖用于糖缀合物生物合成

Damerow Sebastian, Hoppe Carolin, Bandini Giulia, Zarnovican Patricia, Buettner Falk F R, Ferguson Michael A J, Routier Françoise H