Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice
消除前层粘蛋白A的ZMPSTE24切割位点会导致小鼠出现早衰表型,但寿命接近正常。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2118695119
Wang, Yuexia; Shilagardi, Khurts; Hsu, Trunee; Odinammadu, Kamsi O; Maruyama, Takamitsu; Wu, Wei; Lin, Chyuan-Sheng; Damoci, Christopher B; Spear, Eric D; Shin, Ji-Yeon; Hsu, Wei; Michaelis, Susan; Worman, Howard J