Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer
Luribinectedin 通过激活小细胞肺癌中的 STING-IFN 信号通路来增强 PD-L1 阻断疗法的敏感性
期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.101944
Chakraborty, Subhamoy; Sen, Utsav; Ventura, Kedwin; Jethalia, Vrinda; Coleman, Charles; Sridhar, Subhasree; Banerjee, Avisek; Ozakinci, Hilal; Mahendravarman, Yazhini; Snioch, Konrad; de Stanchina, Elisa; Shields, Misty D; Tomalin, Lewis E; Demircioglu, Deniz; Boyle, Theresa A; Tocheva, Anna; Hasson, Dan; Sen, Triparna
肺癌
肿瘤
肿瘤免疫
信号转导
STING
PD-L1
细胞生物学
