日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PARP1 and PARP2 are dispensable for DNA repair by microhomology-mediated end-joining at double-ended DSBs.

PARP1 和 PARP2 对于通过微同源介导的末端连接修复双端 DSB 的 DNA 损伤来说并非必需。

Ortega Raquel, Taylor Erin R, Whitehead Sophie M, Danhorn Thomas, Bitler Benjamin G, Arnoult Nausica

Tumor-infiltrating T Lymphocytes Recognize Thyroid-specific Proteins and Neo-antigens in Follicular Cell-derived Thyroid Cancers

肿瘤浸润性T淋巴细胞识别滤泡细胞来源的甲状腺癌中的甲状腺特异性蛋白和新抗原

Garza, Breaunna; Calhoun, Jacob; Norman, Paul J; Cline, Noah; Kichula, Katherine M; Farias, Ticiana D J; Sams, Sharon; Boorgula, Meher Preethi; Danhorn, Thomas; Haugen, Bryan R; French, Jena D

SM08502-Mediated β-Catenin Repression Synergizes with Olaparib to Inhibit Tumor Progression.

SM08502 介导的 β-catenin 抑制与奥拉帕尼协同作用抑制肿瘤进展。

Corr Bradley R, Woodruff Elizabeth R, Yamamoto Tomomi M, Jordan Kimberly R, Danhorn Thomas, Bossard Carine, Nguyen Lily L, Chuong Edward B, Wick Lars, Young Alexandra, Kusumoto Shinya, Orsulic Sandra, Barroilhet Lisa, Bitler Benjamin G

PARP1 and PARP2 are dispensable for DNA repair by microhomology-mediated end-joining during mitosis.

在有丝分裂过程中,PARP1 和 PARP2 对于通过微同源介导的末端连接进行 DNA 修复来说并非必需

Ortega Raquel, Taylor Erin, Whitehead Sophie M, Danhorn Thomas, Bitler Benjamin G, Arnoult Nausica

MIG6 Mediates Adaptive and Acquired Resistance to ALK/ROS1 Fusion Kinase Inhibition through EGFR Bypass Signaling

MIG6 通过 EGFR 旁路信号传导介导对 ALK/ROS1 融合激酶抑制的适应性和获得性抗性

Nan Chen, Logan C Tyler, Anh T Le, Eric A Welsh, Bin Fang, Andrew Elliott, Kurtis D Davies, Thomas Danhorn, Gregory J Riely, Marc Ladanyi, Eric B Haura, Robert C Doebele

Examination of Wnt signaling as a therapeutic target for pancreatic ductal adenocarcinoma (PDAC) using a pancreatic tumor organoid library (PTOL).

利用胰腺肿瘤类器官库(PTOL)研究Wnt信号通路作为胰腺导管腺癌(PDAC)治疗靶点的作用

Hawkins Hayley J, Yacob Betelehem W, Brown Monica E, Goldstein Brandon R, Arcaroli John J, Bagby Stacey M, Hartman Sarah J, Macbeth Morgan, Goodspeed Andrew, Danhorn Thomas, Lentz Robert W, Lieu Christopher H, Leal Alexis D, Messersmith Wells A, Dempsey Peter J, Pitts Todd M

Tumor-Intrinsic Activity of Chromobox 2 Remodels the Tumor Microenvironment in High-grade Serous Carcinoma

Chromobox 2 的肿瘤内在活性重塑了高级别浆液性癌中的肿瘤微环境

Ritsuko Iwanaga, Tomomi M Yamamoto, Karina Gomez, Lily L Nguyen, Elizabeth R Woodruff, Miriam D Post, Railey G Mikeska, Etienne Danis, Thomas Danhorn, Meher P Boorgula, Siddhartha S Mitra, Nicole A Marjon, Benjamin G Bitler, Lindsay W Brubaker

Reduced Progenitor Function and Altered Immune Landscape Contribute to Field Cancerization of Lung Adenocarcinoma

祖细胞功能降低和免疫微环境改变导致肺腺癌发生癌变。

Assante, Alexis; Lkhagvadorj, Khosbayar; Clambey, Eric T; Danhorn, Thomas; Merrick, Daniel T; Keith, Robert L; New, Melissa L; Degregori, James; Miller, York E; Ghosh, Moumita

Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1-mutated endometrial cancer

CTNNB1 突变子宫内膜癌的 CDC 样激酶抑制 (CLK)/双特异性酪氨酸调节激酶 (DYRK) 和紫杉烷联合治疗

Bradley R Corr, Marisa R Moroney, Elizabeth Woodruff, Zachary L Watson, Kimberly R Jordan, Thomas Danhorn, Courtney Bailey, Rebecca J Wolsky, Benjamin G Bitler

Heightened turnover and failed maturation of monocyte-derived macrophages in murine chronic granulomatous disease

小鼠慢性肉芽肿病中单核细胞来源巨噬细胞的周转率升高和成熟障碍

Gibbings, Sophie L; Haist, Kelsey C; Nick, Heidi; Frasch, S Courtney; Glass, Teagan H; Vestal, Brian; Danhorn, Thomas; Mould, Kara J; Henson, Peter M; Bratton, Donna L