日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intranasal replicating adenovirus type 4-vectored SARS-CoV-2 vaccines induce durable and efficacious responses in preclinical testing

鼻内复制型4型腺病毒载体SARS-CoV-2疫苗在临床前试验中诱导了持久有效的免疫应答

Kim, Breanna; Roenicke, Rachel; Roeder, Peyton M; Steinberg, Isabel; Patamawenu, Andy; Harrison, Mitra; Veer, Freya Van't; Koory, Emma; Xie, Jane; Shofner, Tulley; Matsuda, Kenta; Wettstein, Eleanor; Ober, Ellison; Cooney, Ceanna; Kim, Tae; Webber, Jonathan D; Meeks, Tyler; Park, Chung; Burdette, Tracey; Georgia, Shalamar; Readler, James M; Vostal, Alexander C; Hostal, Anna; Cohen, Jeffrey I; Gagne, Matthew; Ziff, Zohar; Richard, Ketan; Burnett, Matthew R; Maule, Erin; Callier, Viviane; Liang, Jason; Kovacikova, Gabriela; Souter, Scarlett C; Weiner, Joshua A; Douek, Daniel; Ackerman, Margaret E; Wright, Peter F; Johnson, Reed F; Connors, Mark

Intranasal Replicating Adenovirus type 4-SARS-CoV-2 Recombinants Induce Superior Immune Response Durability and Efficacy in Preclinical Testing Compared to Standard Intramuscular Vaccines

鼻内复制型4型SARS-CoV-2重组疫苗在临床前试验中比标准肌肉注射疫苗诱导更持久、更有效的免疫反应。

Kim, Breanna; Roenicke, Rachel; Roeder, Peyton M; Steinberg, Isabel; Patamawenu, Andy; Harrison, Mitra; Veer, Freya Van't; Koory, Emma; Xie, Jane; Shofner, Tulley; Matsuda, Kenta; Wettstein, Eleanor; Ober, Ellison; Cooney, Ceanna; Kim, Tae; Webber, Jonathan D; Meeks, Tyler; Burdette, Tracey; Clark, Shalamar G; Vostal, Alexander C; Hostal, Anna; Cohen, Jeffrey I; Gagne, Matthew; Ziff, Zohar; Richard, Ketan; Burnett, Matthew R; Maule, Erin; Callier, Viviane; Liang, Jason; Kovacikova, Gabriela; Souter, Scarlett C; Weiner, Joshua A; Douek, Daniel; Ackerman, Margaret E; Wright, Peter F; Johnson, Reed F; Connors, Mark

Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G

利用 Vif 抗性的 APOBEC3G 开发用于 HIV-1 基因治疗的慢病毒载体

Krista A Delviks-Frankenberry, Daniel Ackerman, Nina D Timberlake, Maria Hamscher, Olga A Nikolaitchik, Wei-Shau Hu, Bruce E Torbett, Vinay K Pathak

Establishment of hepatocellular carcinoma patient-derived xenografts from image-guided percutaneous biopsies

通过影像引导经皮活检建立肝细胞癌患者异种移植模型

David J Tischfield, Daniel Ackerman, Michael Noji, James X Chen, Omar Johnson, Nicholas R Perkons, Gregory J Nadolski, Stephen J Hunt, Michael C Soulen, Emma E Furth, Terence P Gade

Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity

精氨酸酶2通过消耗生物合成辅因子磷酸吡哆醛和增加多胺毒性来抑制肾癌进展

Joshua D Ochocki ,Sanika Khare ,Markus Hess ,Daniel Ackerman ,Bo Qiu ,Jennie I Daisak ,Andrew J Worth ,Nan Lin ,Pearl Lee ,Hong Xie ,Bo Li ,Bradley Wubbenhorst ,Tobi G Maguire ,Katherine L Nathanson ,James C Alwine ,Ian A Blair ,Itzhak Nissim ,Brian Keith ,M Celeste Simon

Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation

甘油三酯通过平衡脂肪酸饱和度促进缺氧应激期间脂质稳态

Daniel Ackerman, Sergey Tumanov, Bo Qiu, Evdokia Michalopoulou, Michelle Spata, Andrew Azzam, Hong Xie, M Celeste Simon, Jurre J Kamphorst

Electrolytic ablation enables cancer cell targeting through pH modulation

电解消融通过调节 pH 值实现癌细胞靶向

Nicholas R Perkons, Elliot J Stein, Chike Nwaezeapu, Joseph C Wildenberg, Kamiel Saleh, Roni Itkin-Ofer, Daniel Ackerman, Michael C Soulen, Stephen J Hunt, Gregory J Nadolski, Terence P Gade

HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma

HIF2α 依赖性脂质储存促进透明细胞肾细胞癌中的内质网稳态

Bo Qiu, Daniel Ackerman, Danielle J Sanchez, Bo Li, Joshua D Ochocki, Alison Grazioli, Ekaterina Bobrovnikova-Marjon, J Alan Diehl, Brian Keith, M Celeste Simon

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress

mTORC1 失调导致细胞在肿瘤样应激下严重依赖去饱和脂质生存

Regina M Young, Daniel Ackerman, Zachary L Quinn, Anthony Mancuso, Michaela Gruber, Liping Liu, Dionysios N Giannoukos, Ekaterina Bobrovnikova-Marjon, J Alan Diehl, Brian Keith, M Celeste Simon

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Sir2 过表达对秀丽隐杆线虫和果蝇的寿命没有影响

Camilla Burnett, Sara Valentini, Filipe Cabreiro, Martin Goss, Milán Somogyvári, Matthew D Piper, Matthew Hoddinott, George L Sutphin, Vid Leko, Joshua J McElwee, Rafael P Vazquez-Manrique, Anne-Marie Orfila, Daniel Ackerman, Catherine Au, Giovanna Vinti, Michèle Riesen, Ken Howard, Christian Neri,