M102 activates both NRF2 and HSF1 transcription factor pathways and is neuroprotective in cell and animal models of amyotrophic lateral sclerosis
M102 可激活 NRF2 和 HSF1 转录因子通路，并在肌萎缩侧索硬化症的细胞和动物模型中发挥神经保护作用。
期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/s13024-025-00908-y
Keerie, Amy F; Martins, Raquel Rua; Allen, Chloe F; Bowden, Katie; Al Mashhadi, Sufana; Marlow, Thomas; Myszczynska, Monika; Thakur, Nikitha; Beal, Selina N; Shaw, Allan; Suresh, Shivani; McKinnon, Scott N; Cooper-Knock, Johnathan; West, Ryan J H; Bonsall, Sam; Daniel, Alex; Wells, Tyler; Kumar, Vedanth; Ellis, Brittany C S; Higgins, Maureen; Dinkova-Kostova, Albena T; Shelkovnikova, Tatyana A; Kalfus, Ira N; Shan, Ning; Shaw, Pamela J; Ferraiuolo, Laura; Mead, Richard J
