日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Effect of simvastatin on postoperative complications in patients undergoing one-lung ventilation during surgery: the Prevention HARP-2 randomised controlled trial

辛伐他汀对单肺通气手术患者术后并发症的影响：Prevention HARP-2随机对照试验

期刊:Thorax
影响因子:7.7
doi:10.1136/thorax-2025-223072
Glass, Adam; O'Kane, Cecilia M; Dhrampal, Akesh; Fontaine, Eustace; Ryan, James; Loubani, Mahmoud; Rathinam, Sridhar; Naidu, Babu; Welters, Ingeborg D; Silversides, Jon; Alkhaffar, Bilal; Hayden, Jeremy; Griffiths, Ewen; Chan, David; Doran, Annmarie; Toase, Sorcha; Campbell, Christina; Agus, Ashley; Perkins, Gavin D; McAuley, Daniel Francis; Shyamsundar, Murali
发表日期：2026
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SHORTER trial: protocol for a pragmatic, multicentre, randomised controlled trial of short-duration antibiotic therapy for critically ill patients with sepsis

SHORTER试验：一项针对脓毒症危重患者的短期抗生素治疗的实用性、多中心、随机对照试验方案

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2026-117142
Mawson, Phil; Morton, Miranda; Walmsley, Zoe; Wafer, Rebecca; Hancock, Helen C; Mossop, Helen; Al-Ashmori, Sarah; Emerson, Lydia M; Smith, Jamie; Colquhoun, Gosha; Wu, Hangjian; Fernandez-Garcia, Cristina; Ternent, Laura; Kumar, Rashmi; Ogden, Margaret; Loraine, Laura; Taylor, Leia; Ndlovu, Sipho; Hall, Phil; Gordon, Anthony C; Rostron, Anthony; McMullan, Ronan; Felton, Tim; Walsh, Timothy; McAuley, Daniel Francis; Dark, Paul; Simpson, A John; Hellyer, Thomas P
炎症/感染
败血症
发表日期：2026
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Effects of Hyperoxia on Pulmonary Inflammation and organ injury in a human in vivo model (HIPI): study protocol of a randomised, double-blind, placebo-controlled trial

高氧对人体体内模型（HIPI）肺部炎症和器官损伤的影响：一项随机、双盲、安慰剂对照试验的研究方案

期刊:Bmj Open Respiratory Research
影响因子:3.4
doi:10.1136/bmjresp-2024-002393
Linden, Dermot; Dorrian, Delia; Tandel, Shikha; McKelvey, Michael; Bailey, Melanie; Conlon, John; Moore, David; Carr, Sharon; Taggart, Clifford C; Bradley, Judy M; Kidney, Joseph; OKane, Cecilia M; McAuley, Daniel Francis
肺炎
Immunology/Inflammation
炎症/感染
炎症
发表日期：2025
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Development and validation of an LC-MS/MS method for the quantification of novel therapeutic TT-478, a selective adenosine receptor 2B antagonist, for a phase I/II clinical trial

开发并验证一种用于定量分析新型治疗药物 TT-478（一种选择性腺苷受体 2B 拮抗剂）的 LC-MS/MS 方法，用于 I/II 期临床试验

期刊:Bioanalysis
影响因子:1.8
doi:10.1080/17576180.2025.2554564
Whitaker, Daniel; Francis, Laura; Karaborni, Sami; Smith, Steven; Craigen, Jenny L; Svetlik, Svatopluk; Barnett, Shelby; Veal, Gareth J
信号转导
多发性硬化症
免疫/内分泌
发表日期：2025
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Novel Peptide Therapeutics Targeting the L-Type Calcium Channel Prevent Hypertrophic Cardiomyopathy by Decreasing Mitochondrial Energetics

靶向L型钙通道的新型肽类疗法通过降低线粒体能量消耗来预防肥厚型心肌病

期刊:Jacc-Basic To Translational Science
影响因子:
doi:10.1016/j.jacbts.2025.04.006
Er, Teagan S; Reinke, Daniel; Francis, Alice J; Solomon, Tanya M; Viola, Helena M; Szappanos, Henrietta Cserne; Richworth, Caitlyn M; Jenkins, Catherine; Camacho Londoño, Juan E; Ponnuswamy, Padmapriya; McFarlane, Ciaran; Van Petegem, Filip; Hool, Livia C
心血管
线粒体
心肌病
发表日期：2025
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Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes

利用血浆细胞因子及其调节因子对脓毒症患者进行分层：与预后、治疗效果和白细胞转录组亚表型的关系

期刊:Thorax
影响因子:7.7
doi:10.1136/thorax-2023-220538
Antcliffe, David Benjamin; Mi, Yuxin; Santhakumaran, Shalini; Burnham, Katie L; Prevost, A Toby; Ward, Josie K; Marshall, Timothy J; Bradley, Claire; Al-Beidh, Farah; Hutton, Paula; McKechnie, Stuart; Davenport, Emma E; Hinds, Charles J; O'Kane, Cecilia M; McAuley, Daniel Francis; Shankar-Hari, Manu; Gordon, Anthony C; Knight, Julian C
炎症/感染
细胞生物学
败血症
免疫/内分泌
发表日期：2024
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Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS).

IL-18 介导的铁蛋白升高与急性呼吸窘迫综合征 (ARDS) 的全身炎症和死亡率相关

期刊:Thorax
影响因子:7.7
doi:10.1136/thorax-2023-220292
Mehta Puja, Samanta Romit J, Wick Katherine, Coll Rebecca C, Mawhinney Thea, McAleavey Patrick G, Boyle Andrew J, Conlon John, Shankar-Hari Manu, Rogers Angela, Calfee Carolyn S, Matthay Michael A, Summers Charlotte, Chambers Rachel Clare, McAuley Daniel Francis, O'Kane Cecilia M
炎症/感染
炎症
发表日期：2024
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SIGNET: protocol for a multicentre, single-blind prospective, group sequential, randomised controlled trial to evaluate the benefits of a single dose of simvastatin given to potential organ donors declared dead by neurological criteria on outcomes in organ recipients

SIGNET：一项多中心、单盲、前瞻性、组序贯、随机对照试验方案，旨在评估对根据神经学标准宣布死亡的潜在器官捐献者给予单剂量辛伐他汀对器官受者预后的益处。

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2024-086352
Evans, Amy; Mawson, Phil; Thomas, Helen; Keen, Katie; Watson, Christopher Je; McAuley, Daniel Francis; MacGowan, Guy A; Sheerin, Neil S; Fisher, Andrew; Shaw, James; Yates, Hilary; Fallow, Andrea; Kounali, Daphne; Banks, Jennifer; Stevens, Margaret; Paul, Roshni; Hodge, Renate; Lawson, Emma; Harvey, Dan; Dark, John
发表日期：2024
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Estimating the attributable fraction of mortality from acute respiratory distress syndrome to inform enrichment in future randomised clinical trials

估算急性呼吸窘迫综合征导致的死亡比例，以指导未来随机临床试验的优化。

期刊:Thorax
影响因子:7.7
doi:10.1136/thorax-2023-220262
Saha, Rohit; Pham, Tài; Sinha, Pratik; Maddali, Manoj V; Bellani, Giacomo; Fan, Eddy; Summers, Charlotte; Douiri, Abdel; Rubenfeld, Gordon D; Calfee, Carolyn S; Laffey, John Gerard; McAuley, Daniel Francis; Shankar-Hari, Manu
发表日期：2023
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Inhibition of bradykinin in SARS-CoV-2 infection: a randomised, double-blind trial of icatibant compared with placebo (ICASARS)

SARS-CoV-2 感染中缓激肽的抑制：icatibant 与安慰剂的随机、双盲试验 (ICASARS)

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2023-074726
Bailey, Melanie; Linden, Dermot; Earley, Olivia; Guo Parke, Hong; McAuley, Daniel Francis; Peto, Tunde; Taggart, Cliff; Kidney, Joe
SARS-CoV-2
炎症/感染
发表日期：2023
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