Daniel H Fowler相关文献与解析，生知库 | 链接生命科学的每一步

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

PD-1 抑制受体下调天冬酰胺酰内肽酶并维持诱导调节性 T 细胞中的 Foxp3 转录因子稳定性

doi:10.1016/j.immuni.2018.05.006

Chaido Stathopoulou, Arunakumar Gangaplara, Grace Mallett, Francis A Flomerfelt, Lukasz P Liniany, David Knight, Leigh A Samsel, Rolando Berlinguer-Palmini, Joshua J Yim, Tania C Felizardo, Michael A Eckhaus, Laura Edgington-Mitchell, Jonathan Martinez-Fabregas, Jinfang Zhu, Daniel H Fowler, Sander

PD-1 regulates KLRG1+ group 2 innate lymphoid cells

PD-1 调节 KLRG1+ 第 2 组先天淋巴细胞

期刊:Journal of Experimental Medicine

影响因子:12.6

doi:10.1084/jem.20161653

Samuel Taylor, Yuefeng Huang, Grace Mallett, Chaido Stathopoulou, Tania C Felizardo, Ming-An Sun, Evelyn L Martin, Nathaniel Zhu, Emma L Woodward, Martina S Elias, Jonathan Scott, Nick J Reynolds, William E Paul, Daniel H Fowler, Shoba Amarnath

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps

可以通过工程化的受体信号钳来微调白细胞介素-2 的活性

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2015.04.018

Suman Mitra, Aaron M Ring, Shoba Amarnath, Jamie B Spangler, Peng Li, Wei Ju, Suzanne Fischer, Jangsuk Oh, Rosanne Spolski, Kipp Weiskopf, Holbrook Kohrt, Jason E Foley, Sumati Rajagopalan, Eric O Long, Daniel H Fowler, Thomas A Waldmann, K Christopher Garcia, Warren J Leonard

Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo

骨髓间充质基质细胞利用嘌呤信号在体内耐受人类 Th1 细胞

期刊:Stem Cells

影响因子:4

doi:10.1002/stem.1934

Shoba Amarnath, Jason E Foley, Don E Farthing, Ronald E Gress, Arian Laurence, Michael A Eckhaus, Jean-Yves Métais, Jeremy J Rose, Frances T Hakim, Tania C Felizardo, Austin V Cheng, Pamela G Robey, David E Stroncek, Marianna Sabatino, Minoo Battiwalla, Sawa Ito, Daniel H Fowler, Austin J Barrett

Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation

低强度异基因造血细胞移植后雷帕霉素耐药供体 CD4+ Th2/Th1（T-Rapa）细胞的 2 期临床试验

期刊:Blood

影响因子:21

doi:10.1182/blood-2012-08-446872

Daniel H Fowler, Miriam E Mossoba, Seth M Steinberg, David C Halverson, David Stroncek, Hahn M Khuu, Frances T Hakim, Luciano Castiello, Marianna Sabatino, Susan F Leitman, Jacopo Mariotti, Juan C Gea-Banacloche, Claude Sportes, Nancy M Hardy, Dennis D Hickstein, Steven Z Pavletic, Scott Rowley, And

Harnessing autophagy for cell fate control gene therapy

利用自噬进行细胞命运控制基因治疗

期刊:Autophagy

影响因子:14.6

doi:10.4161/auto.24639

Tania C Felizardo, Jason Foley, Kevin Steed, Boro Dropulic, Shoba Amarnath, Jeffrey A Medin, Daniel H Fowler

Differential gene expression profile of first-generation and second-generation rapamycin-resistant allogeneic T cells

第一代与第二代雷帕霉素耐药同种异体T细胞的差异基因表达谱

期刊:Cytotherapy

影响因子:3.7

doi:10.1016/j.jcyt.2012.12.008

Luciano Castiello, Miriam Mossoba, Antonella Viterbo, Marianna Sabatino, Vicki Fellowes, Jason E Foley, Matthew Winterton, David C Halverson, Sara Civini, Ping Jin, Daniel H Fowler, David F Stroncek

Rapamycin resistant murine th9 cells have a stable in vivo phenotype and inhibit graft-versus-host reactivity

雷帕霉素抗性的小鼠 th9 细胞具有稳定的体内表型并抑制移植物抗宿主反应

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0072305

Courtney W Mangus, Paul R Massey, Daniel H Fowler, Shoba Amarnath

STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease

STAT3 转录因子促进 nTreg 细胞不稳定并限制急性鼠移植物抗宿主病期间 iTreg 细胞的产生

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2012.05.027

Arian Laurence, Shoba Amarnath, Jacopo Mariotti, Yong Chan Kim, Jason Foley, Michael Eckhaus, John J O'Shea, Daniel H Fowler

Autologous, lentivirus-modified, T-rapa cell "micropharmacies" for lysosomal storage disorders

用于治疗溶酶体贮积症的自体慢病毒修饰的T-rapa细胞“微型药房”

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

PD-1 抑制受体下调天冬酰胺酰内肽酶并维持诱导调节性 T 细胞中的 Foxp3 转录因子稳定性

PD-1 regulates KLRG1+ group 2 innate lymphoid cells

PD-1 调节 KLRG1+ 第 2 组先天淋巴细胞

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps

可以通过工程化的受体信号钳来微调白细胞介素-2 的活性

Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo

骨髓间充质基质细胞利用嘌呤信号在体内耐受人类 Th1 细胞

Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation

低强度异基因造血细胞移植后雷帕霉素耐药供体 CD4+ Th2/Th1（T-Rapa）细胞的 2 期临床试验

Harnessing autophagy for cell fate control gene therapy

利用自噬进行细胞命运控制基因治疗

Differential gene expression profile of first-generation and second-generation rapamycin-resistant allogeneic T cells

第一代与第二代雷帕霉素耐药同种异体T细胞的差异基因表达谱

Rapamycin resistant murine th9 cells have a stable in vivo phenotype and inhibit graft-versus-host reactivity

雷帕霉素抗性的小鼠 th9 细胞具有稳定的体内表型并抑制移植物抗宿主反应

STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease

STAT3 转录因子促进 nTreg 细胞不稳定并限制急性鼠移植物抗宿主病期间 iTreg 细胞的产生