日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons

Kappa 阿片受体诱导的厌恶需要 VTA 多巴胺神经元中的 p38 MAPK 激活

Jonathan M Ehrich, Daniel I Messinger, Cerise R Knakal, Jamie R Kuhar, Selena S Schattauer, Michael R Bruchas, Larry S Zweifel, Brigitte L Kieffer, Paul E M Phillips, Charles Chavkin

Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake

压力会产生厌恶情绪,并通过释放腹侧纹状体中的内源性强啡肽来局部刺激血清素再摄取,从而增强可卡因的奖励作用

Abigail G Schindler, Daniel I Messinger, Jeffrey S Smith, Haripriya Shankar, Richard M Gustin, Selena S Schattauer, Julia C Lemos, Nicholas W Chavkin, Catherine E Hagan, John F Neumaier, Charles Chavkin

Repeated stress dysregulates κ-opioid receptor signaling in the dorsal raphe through a p38α MAPK-dependent mechanism

反复应激通过 p38α MAPK 依赖机制导致背缝中的 κ-阿片受体信号失调

Julia C Lemos, Clarisse A Roth, Daniel I Messinger, Harminder K Gill, Paul E M Phillips, Charles Chavkin