日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Blockade of TGF-β and PD-L1 by bintrafusp alfa promotes survival in preclinical ovarian cancer models by promoting T effector and NK cell responses

bintrafusp alfa 通过促进 T 效应细胞和 NK 细胞反应,阻断 TGF-β 和 PD-L1,从而提高临床前卵巢癌模型的生存率。

Jacob Kment # ,Daniel Newsted # ,Stephanie Young ,Michael C Vermeulen ,Brian J Laight ,Peter A Greer ,Yan Lan ,Andrew W Craig

Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis

针对关节炎的广谱交叉反应性趋化因子阻断抗体的定向进化

Alessandro Angelini,Yoshishige Miyabe,Daniel Newsted,Byron H Kwan,Chie Miyabe,Ryan L Kelly,Misha N Jamy,Andrew D Luster,K Dane Wittrup

MicroRNA-206 suppresses TGF-β signalling to limit tumor growth and metastasis in lung adenocarcinoma

MicroRNA-206 抑制 TGF-β 信号传导以限制肺腺癌的肿瘤生长和转移

Kathleen Watt, Daniel Newsted, Elena Voorand, Robert J Gooding, Adrianna Majewski, Peter Truesdell, Binchen Yao, Thomas Tuschl, Neil Renwick, Andrew W Craig

Blockade of TGF-β signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models

使用新型合成抗体阻断 TGF-β 信号传导可限制免疫排斥并改善转移性卵巢癌模型中的化疗反应

Daniel Newsted, Sunandan Banerjee, Kathleen Watt, Sarah Nersesian, Peter Truesdell, Levi L Blazer, Lia Cardarelli, Jarrett J Adams, Sachdev S Sidhu, Andrew W Craig

A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models

针对 MMP-14 的新型免疫疗法可限制三阴性乳腺癌模型中的缺氧、免疫抑制和转移

Binbing Ling, Kathleen Watt, Sunandan Banerjee, Daniel Newsted, Peter Truesdell, Jarrett Adams, Sachdev S Sidhu, Andrew W B Craig