日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Early-Life Climbing Stratifies the Metabolome and Mortality Risk in Genetically Identical Flies

早期攀爬行为会影响基因相同的果蝇的代谢组和死亡风险。

Harrison, Benjamin R; Sun, Yangxi; Nonacs, Tom; Shankar, Harini; Djukovic, Danijel; Raftery, Daniel; Promislow, Daniel E L

Systems biology approaches identify metabolic signatures of dietary lifespan and healthspan across species

系统生物学方法可以识别不同物种的饮食寿命和健康寿命的代谢特征。

Hilsabeck, Tyler A U; Narayan, Vikram P; Wilson, Kenneth A; Carrera, Enrique M; Raftery, Daniel; Promislow, Daniel; Brem, Rachel B; Campisi, Judith; Kapahi, Pankaj

Natural variation in age-related dopamine neuron degeneration is glutathione dependent and linked to life span

与年龄相关的多巴胺神经元退化的自然变异依赖于谷胱甘肽,并且与寿命有关。

Coleman, Colin R; Pallos, Judit; Arreola-Bustos, Alicia; Wang, Lu; Raftery, Daniel; Promislow, Daniel E L; Martin, Ian

Wide-ranging genetic variation in sensitivity to rapamycin in Drosophila melanogaster

果蝇对雷帕霉素敏感性的广泛遗传变异

Harrison, Benjamin R; Lee, Mitchell B; Zhang, Shufan; Young, Bill; Han, Kenneth; Sukomol, Jiranut; Paus, Vanessa; Tran, Sarina; Kim, David; Fitchett, Hannah; Pan, Yu-Chen; Tesfaye, Philmon; Johnson, Alia W; Zhao, Xiaqing; Djukovic, Danijel; Raftery, Daniel; Promislow, Daniel E L

A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response

对果蝇嘌呤代谢物的 GWAS 关联分析识别出人类 FAM214 同源物 medusa,它以保守的方式通过调节嘌呤代谢和炎症反应来增强高尿酸血症引起的病理

Tyler A U Hilsabeck, Ru Liu-Bryan, Tracy Guo, Kenneth A Wilson, Neelanjan Bose, Daniel Raftery, Jennifer N Beck, Sven Lang, Kelly Jin, Christopher S Nelson, Tal Oron, Marshall Stoller, Daniel Promislow, Rachel B Brem, Robert Terkeltaub, Pankaj Kapahi4

Modular Evolution of the Drosophila Metabolome

果蝇代谢组的模块化进化

Harrison, Benjamin R; Hoffman, Jessica M; Samuelson, Ariana; Raftery, Daniel; Promislow, Daniel E L

Age-Independent Cardiac Protection by Pharmacological Activation of Beclin-1 During Endotoxemia and Its Association With Energy Metabolic Reprograming in Myocardium-A Targeted Metabolomics Study

内毒血症期间通过药理学激活 Beclin-1 实现的与年龄无关的心脏保护及其与心肌能量代谢重编程的关系——一项靶向代谢组学研究

Matthew Kim, Azadeh Nikouee, Raymond Zou, Di Ren, Zhibin He, Ji Li, Lu Wang, Danijel Djukovic, Daniel Raftery, Hayley Purcell, Daniel Promislow, Yuxiao Sun, Mohammad Goodarzi, Qing-Jun Zhang, Zhi-Ping Liu, Qun Sophia Zang

Resilience integrates concepts in aging research

复原力整合了衰老研究中的概念

Daniel Promislow, Rozalyn M Anderson, Marten Scheffer, Bernard Crespi, James DeGregori, Kelley Harris, Barbara Natterson Horowitz, Morgan E Levine, Maria A Riolo, David S Schneider, Sabrina L Spencer, Dario Riccardo Valenzano, Michael E Hochberg

KL1 Domain of Longevity Factor Klotho Mimics the Metabolome of Cognitive Stimulation and Enhances Cognition in Young and Aging Mice.

长寿因子 Klotho 的 KL1 结构域模拟认知刺激的代谢组,增强年轻和老年小鼠的认知能力

Gupta Shweta, Moreno Arturo J, Wang Dan, Leon Julio, Chen Chen, Hahn Oliver, Poon Yan, Greenberg Kenneth, David Nathaniel, Wyss-Coray Tony, Raftery Daniel, Promislow Daniel E L, Dubal Dena B

Negative Association of Smoking History With Clinically Manifest Cardiac Sarcoidosis: A Case-Control Study

吸烟史与临床表现型心脏结节病呈负相关:一项病例对照研究

Xu, Chenchen; Nery, Pablo B; Wiefels, Christiane; Beanlands, Rob S; Spence, Stewart D; Juneau, Daniel; Promislow, Steven; Boczar, Kevin; deKemp, Robert A; Birnie, David H