SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
SIRT1 对 SAMHD1 的去乙酰化作用通过促进 DNA 与双链断裂处的结合来促进 DNA 末端切除。
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-022-34578-x
Priya Kapoor-Vazirani ,Sandip K Rath ,Xu Liu ,Zhen Shu ,Nicole E Bowen ,Yitong Chen ,Ramona Haji-Seyed-Javadi ,Waaqo Daddacha ,Elizabeth V Minten ,Diana Danelia ,Daniela Farchi ,Duc M Duong ,Nicholas T Seyfried ,Xingming Deng ,Eric A Ortlund ,Baek Kim ,David S Yu
