日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of mitochondrial Ca2+ uptake protein 3 impairs skeletal muscle calcium handling and exercise capacity

线粒体 Ca2+ 摄取蛋白 3 的缺失会损害骨骼肌钙处理和运动能力

Barbara Roman, Yusuf Mastoor, Yingfan Zhang, Dennis Gross, Danielle Springer, Chengyu Liu, Brian Glancy, Elizabeth Murphy

Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischaemia- reperfusion injury

Ogfod1 缺失可增加心脏 β-丙氨酸水平并保护小鼠免受缺血再灌注损伤

Michael Harris, Junhui Sun, Karen Keeran, Angel Aponte, Komudi Singh, Danielle Springer, Marjan Gucek, Mehdi Pirooznia, Matthew E Cockman, Elizabeth Murphy, Leslie M Kennedy

Cardiac specific knock-down of peroxisome proliferator activated receptor α prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2

过氧化物酶体增殖激活受体α的心脏特异性敲低可防止禁食引起的心脏脂质积累并降低周脂素2

Natasha Fillmore, Vincent Hou, Junhui Sun, Danielle Springer, Elizabeth Murphy

Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA

小鼠印迹缺失模型中的心脏病变是由于 H19 长链非编码 RNA 的错误表达造成的

Ki-Sun Park #, Beenish Rahat #, Hyung Chul Lee, Zu-Xi Yu, Jacob Noeker, Apratim Mitra, Connor M Kean, Russell H Knutsen, Danielle Springer, Claudia M Gebert, Beth A Kozel, Karl Pfeifer

Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice

神经元特异性消融 eIF5A 或脱氧羟脯氨酸合酶会导致小鼠生长、活力、神经发育和认知功能受损

Rajesh Kumar Kar, Ashleigh S Hanner, Matthew F Starost, Danielle Springer, Teresa L Mastracci, Raghavendra G Mirmira, Myung Hee Park

PPARγ agonists delay age-associated metabolic disease and extend longevity

PPARγ激动剂可延缓与年龄相关的代谢疾病并延长寿命

Lingyan Xu, Xinran Ma, Narendra Verma, Luce Perie, Jay Pendse, Sama Shamloo, Anne Marie Josephson, Dongmei Wang, Jin Qiu, Mingwei Guo, Xiaodan Ping, Michele Allen, Audrey Noguchi, Danielle Springer, Fei Shen, Caizhi Liu, Shiwei Zhang, Lingyu Li, Jin Li, Junjie Xiao, Jian Lu, Zhenyu Du, Jian Luo, Jos

Systemic Succinate Homeostasis and Local Succinate Signaling Affect Blood Pressure and Modify Risks for Calcium Oxalate Lithogenesis

全身琥珀酸稳态和局部琥珀酸信号传导影响血压并改变草酸钙结石形成的风险

Ahlam Khamaysi, Shireen Anbtawee-Jomaa, Moran Fremder, Hadar Eini-Rider, Liana Shimshilashvili, Sara Aharon, Elina Aizenshtein, Tomer Shlomi, Audrey Noguchi, Danielle Springer, Orson W Moe, Nikolay Shcheynikov, Shmuel Muallem, Ehud Ohana

Human Relaxin-2 Fusion Protein Treatment Prevents and Reverses Isoproterenol-Induced Hypertrophy and Fibrosis in Mouse Heart

人类松弛素-2融合蛋白治疗可预防和逆转异丙肾上腺素诱发的小鼠心脏肥大和纤维化

Junhui Sun, Weidong Hao, Natasha Fillmore, Hanley Ma, Danielle Springer, Zu-Xi Yu, Agnieszka Sadowska, Andrew Garcia, Ruoyan Chen, Vanessa Muniz-Medina, Kim Rosenthal, Jia Lin, Denison Kuruvilla, Jane Osbourn, Sotirios K Karathanasis, Jill Walker, Elizabeth Murphy

Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice

小鼠骨骼肌特异性缺失 β-arrestin-1 和 -2 的代谢影响

Jaroslawna Meister, Derek B J Bone, Grzegorz Godlewski, Ziyi Liu, Regina J Lee, Sergey A Vishnivetskiy, Vsevolod V Gurevich, Danielle Springer, George Kunos, Jürgen Wess

Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype

Casq2 的条件性消融和条件性拯救模型阐明了 Casq2 的发育和细胞类型特异性表达在 CPVT2 表型中的作用

Daniel J Flores, ThuyVy Duong, Luke O Brandenberger, Apratim Mitra, Aditya Shirali, John C Johnson, Danielle Springer, Audrey Noguchi, Zu-Xi Yu, Steven N Ebert, Andreas Ludwig, Bjorn C Knollmann, Mark D Levin, Karl Pfeifer