日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of VU0467319: an M(1) Positive Allosteric Modulator Candidate That Advanced into Clinical Trials

VU0467319 的发现:一种进入临床试验的 M(1) 正向变构调节剂候选药物

Poslunsey, Michael S; Wood, Michael R; Han, Changho; Stauffer, Shaun R; Panarese, Joseph D; Melancon, Bruce J; Engers, Julie L; Dickerson, Jonathan W; Peng, Weimin; Noetzel, Meredith J; Cho, Hyekyung P; Rodriguez, Alice L; Hopkins, Corey R; Morrison, Ryan; Crouch, Rachel D; Bridges, Thomas M; Blobaum, Anna L; Boutaud, Olivier; Daniels, J Scott; Kates, Michael J; Castelhano, Arlindo; Rook, Jerri M; Niswender, Colleen M; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W

Clinical recommendations for polygenic risk score-enhanced breast cancer screening: Can.Heal project

基于多基因风险评分的乳腺癌筛查临床建议:Can.Heal 项目

Bubser, Michael; Bridges, Thomas M; Dencker, Ditte; Gould, Robert W; Grannan, Michael; Noetzel, Meredith J; Lamsal, Atin; Niswender, Colleen M; Daniels, J Scott; Poslusney, Michael S; Melancon, Bruce J; Tarr, James C; Byers, Frank W; Wess, Jürgen; Duggan, Mark E; Dunlop, John; Wood, Michael W; Brandon, Nicholas J; Wood, Michael R; Lindsley, Craig W; Conn, P Jeffrey; Jones, Carrie K; Taha, A; Matt McCrary, J; van Rooij, J; Lahousse, L; Paoletti, F; Pascucci, E; Vaht, M; Pastorino, R; Pezzullo, A M; Boccia, S

Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models

GIRK 激活剂 VU0466551 单独使用及与吗啡联合使用在急性及持续性疼痛模型中的镇痛效果

Abney, Kristopher K; Bubser, Michael; Du, Yu; Kozek, Krystian A; Bridges, Thomas M; Linsdley, Craig W; Daniels, J Scott; Morrison, Ryan D; Wickman, Kevin; Hopkins, Corey R; Jones, Carrie K; Weaver, C David

SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M(4) PAMs

受醛氧化酶 (AO) 代谢启发的 SAR 研究:新型中枢神经系统穿透性三环 M(4) PAM 的发现

Chopko, Trevor C; Han, Changho; Gregro, Alison R; Engers, Darren W; Felts, Andrew S; Poslusney, Mike S; Bollinger, Katrina A; Morrison, Ryan D; Bubser, Michael; Lamsal, Atin; Luscombe, Vincent B; Cho, Hyekyung P; Schnetz-Boutaud, Nathalie C; Rodriguez, Alice L; Chang, Sichen; Daniels, J Scott; Stec, Donald F; Niswender, Colleen M; Jones, Carrie K; Wood, Michael R; Wood, Michael W; Duggan, Mark E; Brandon, Nicholas J; Conn, P Jeffrey; Bridges, Thomas M; Lindsley, Craig W; Melancon, Bruce J

Supratherapeutic Psychotropic Drug Levels in the Emergency Department and Their Association with Delirium Duration: A Preliminary Study

急诊科超治疗浓度精神药物及其与谵妄持续时间的关系:一项初步研究

Han, Jin H; Chen, Alex; Vasilevskis, Eduard E; Schnelle, John F; Ely, E Wesley; Chandrasekhar, Rameela; Morrison, Ryan D; Ryan, Timothy P; Daniels, J Scott; Sutherland, Jeff J; Simmons, Sandra F

Assessment of Patient Medication Adherence, Medical Record Accuracy, and Medication Blood Concentrations for Prescription and Over-the-Counter Medications

评估患者用药依从性、医疗记录准确性以及处方药和非处方药的血药浓度

Sutherland, Jeffrey J; Morrison, Ryan D; McNaughton, Candace D; Daly, Thomas M; Milne, Stephen B; Daniels, J Scott; Ryan, Timothy P

Discovery of 6-(pyrimidin-5-ylmethyl)quinoline-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5

发现 6-(嘧啶-5-基甲基)喹啉-8-甲酰胺类化合物是代谢型谷氨酸受体亚型 5 的负变构调节剂

Felts, Andrew S; Rodriguez, Alice L; Morrison, Ryan D; Blobaum, Anna L; Byers, Frank W; Daniels, J Scott; Niswender, Colleen M; Conn, P Jeffrey; Lindsley, Craig W; Emmitte, Kyle A

A novel in vitro allometric scaling methodology for aldehyde oxidase substrates to enable selection of appropriate species for traditional allometry.

一种新型的醛氧化酶底物体外异速生长标度方法,可用于选择适合传统异速生长的物种

Crouch Rachel D, Hutzler J Matthew, Daniels J Scott

mGlu(7) potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome

mGlu(7) 增强作用可挽救 Rett 综合征小鼠模型的认知、社交和呼吸表型。

Gogliotti, Rocco G; Senter, Rebecca K; Fisher, Nicole M; Adams, Jeffrey; Zamorano, Rocio; Walker, Adam G; Blobaum, Anna L; Engers, Darren W; Hopkins, Corey R; Daniels, J Scott; Jones, Carrie K; Lindsley, Craig W; Xiang, Zixiu; Conn, P Jeffrey; Niswender, Colleen M

Disease-Modifying Effects of M(1) Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model

M(1)毒蕈碱乙酰胆碱受体激活在阿尔茨海默病小鼠模型中的疾病改善作用

Lebois, Evan P; Schroeder, Jason P; Esparza, Thomas J; Bridges, Thomas M; Lindsley, Craig W; Conn, P Jeffrey; Brody, David L; Daniels, J Scott; Levey, Allan I