日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

First-in-human phase 1 dose-escalation study of W0180, an anti-VISTA monoclonal antibody, with and without pembrolizumab in patients with locally advanced or metastatic solid tumours

首次人体1期剂量递增研究,评估抗VISTA单克隆抗体W0180联合或不联合帕博利珠单抗治疗局部晚期或转移性实体瘤患者的疗效。

Gomez-Roca, Carlos; Champiat, Stéphane; Danlos, Francois-Xavier; Castañón Álvarez, Eduardo; Cassier, Philippe Alexandre; Dupuy, Elena; Jegou, David; Primard, Marie; Pétain, Aurélie; Saccareau, Mathilde; Gueguen-Dorbes, Geneviève; Fabre, Claire; Marabelle, Aurélien; Melero, Ignacio

Genome instability and crosstalk with the immune response

基因组不稳定性及其与免疫反应的相互作用

Chabanon, Roman M; Danlos, François-Xavier; Ouali, Kaissa; Postel-Vinay, Sophie

Immune-related adverse events occurring rapidly after a single dose of immune checkpoint blockade

单次注射免疫检查点阻断剂后迅速发生的免疫相关不良事件

Guitton, Romain; Laparra, Ariane; Chanson, Noemie; Champiat, Stephane; Danlos, Francois-Xavier; Michot, Jean-Marie; Messayke, Sabine; Marabelle, Aurelien; Lambotte, Olivier

Expanded senescent CD8 T cells in IMID patients are associated with distinct inflammatory cytokines

IMID患者体内扩增的衰老CD8 T细胞与特定的炎症细胞因子相关

Naigeon, Marie; Bitoun, Samuel; Roulleaux Dugage, Matthieu; de Oliveira, Caroline; Berthot, Caroline; Besse, Benjamin; Marabelle, Aurélien; Danlos, François-Xavier; Mariette, Xavier; Chaput, Nathalie; Nocturne, Gaetane

B cells and the coordination of immune checkpoint inhibitor response in patients with solid tumors

B细胞与实体瘤患者免疫检查点抑制剂反应的协调

Flippot, Ronan; Teixeira, Marcus; Rey-Cardenas, Macarena; Carril-Ajuria, Lucia; Rainho, Larissa; Naoun, Natacha; Jouniaux, Jean-Mehdi; Boselli, Lisa; Naigeon, Marie; Danlos, Francois-Xavier; Escudier, Bernard; Scoazec, Jean-Yves; Cassard, Lydie; Albiges, Laurence; Chaput, Nathalie

Antecedent viral immunization and efficacy of immune checkpoint blockade: an extensive serum antibody profile to predict outcomes in non-small cell lung cancer

既往病毒免疫和免疫检查点阻断的疗效:广泛的血清抗体谱可用于预测非小细胞肺癌的预后

Dall'Olio, Filippo G; Zrafi, Wael Salem; Blampey, Quentin; Danlos, Francois-Xavier; Roulleaux-Dugage, Matthieu; Roman, Gabriel; Naltet, Charles; Cournède, Paul-Henry; Gautheret, Daniel; Aldea, Mihaela; Planchard, David; Barlesi, Fabrice; Marabelle, Aurelien; Hulett, Tyler; Chaput-Gras, Nathalie; Besse, Benjamin

Phase 1 first-in-human dose-escalation study of ANV419 in patients with relapsed/refractory advanced solid tumors

ANV419治疗复发/难治性晚期实体瘤患者的I期首次人体剂量递增研究

Mathiot, Laurent; Combarel, David; Cagnat, Justin; Delahousse, Julia; Ouali, Kaissa; Marabelle, Aurelien; Loriot, Yohann; Ponce, Santiago; Champiat, Stephane; Broutin, Sophie; Danlos, Francois-Xavier

Correction: Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers

更正:对新冠肺炎患者的代谢组学分析揭示了阶段依赖性和预后性生物标志物

Danlos, François-Xavier; Grajeda-Iglesias, Claudia; Durand, Sylvère; Sauvat, Allan; Roumier, Mathilde; Cantin, Delphine; Colomba, Emeline; Rohmer, Julien; Pommeret, Fanny; Baciarello, Giulia; Willekens, Christophe; Vasse, Marc; Griscelli, Frank; Fahrner, Jean-Eudes; Goubet, Anne-Gaëlle; Dubuisson, Agathe; Derosa, Lisa; Nirmalathasan, Nitharsshini; Bredel, Delphine; Mouraud, Séverine; Pradon, Caroline; Stoclin, Annabelle; Rozenberg, Flore; Duchemin, Jérôme; Jourdi, Georges; Ellouze, Syrine; Levavasseur, Françoise; Albigès, Laurence; Soria, Jean-Charles; Barlesi, Fabrice; Solary, Eric; André, Fabrice; Pène, Frédéric; Ackerman, Félix; Mouthon, Luc; Zitvogel, Laurence; Marabelle, Aurélien; Michot, Jean-Marie; Fontenay, Michaela; Kroemer, Guido

Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti-PD-1 + Antiangiogenesis in Malignant Pleural Mesothelioma

基因组不稳定性及促肿瘤炎症与恶性胸膜间皮瘤对PD-1抑制剂+抗血管生成药物的原发性耐药相关

François-Xavier Danlos ,Matthieu Texier ,Bastien Job ,Severine Mouraud ,Lydie Cassard ,Capucine Baldini ,Andrea Varga ,Andrey A Yurchenko ,Audrey Rabeau ,Stéphane Champiat ,Diane Letourneur ,Delphine Bredel ,Sandrine Susini ,Yuna Blum ,Aurelien Parpaleix ,Cedric Parlavecchio ,Lambros Tselikas ,Jean-Eudes Fahrner ,Anne-Gaelle Goubet ,Mathieu Rouanne ,Saloomeh Rafie ,Alae Abbassi ,Ines Kasraoui ,Marie Breckler ,Siham Farhane ,Samy Ammari ,Salim Laghouati ,Anas Gazzah ,Ludovic Lacroix ,Benjamin Besse ,Nathalie Droin ,Marc Deloger ,Sophie Cotteret ,Julien Adam ,Laurence Zitvogel ,Sergey I Nikolaev ,Nathalie Chaput ,Christophe Massard ,Jean-Charles Soria ,Carlos Gomez-Roca ,Gerard Zalcman ,David Planchard ,Aurelien Marabelle

Human virome profiling identified CMV as the major viral driver of a high accumulation of senescent CD8+ T cells in patients with advanced NSCLC

人类病毒组分析显示,CMV 是导致晚期 NSCLC 患者中大量衰老 CD8+ T 细胞积聚的主要病毒驱动因素

Marie Naigeon, Matthieu Roulleaux Dugage, François-Xavier Danlos, Lisa Boselli, Jean-Mehdi Jouniaux, Caroline de Oliveira, Roberto Ferrara, Boris Duchemann, Caroline Berthot, Lou Girard, Ronan Flippot, Laurence Albiges, Siham Farhane, Patrick Saulnier, Ludovic Lacroix, Frank Griscelli, Gabriel Roman