Irbesartan overcomes gemcitabine resistance in pancreatic cancer by suppressing stemness and iron metabolism via inhibition of the Hippo/YAP1/c-Jun axis
厄贝沙坦通过抑制 Hippo/YAP1/c-Jun 轴来抑制干细胞和铁代谢，从而克服胰腺癌对吉西他滨的耐药性
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:11.4
doi:10.1186/s13046-023-02671-8
Tianxing Zhou #, Yongjie Xie #, Xupeng Hou #, Weiwei Bai, Xueyang Li, Ziyun Liu, Quan Man, Jingyan Sun, Danqi Fu, Jingrui Yan, Zhaoyu Zhang, Yifei Wang, Hongwei Wang, Wenna Jiang, Song Gao, Tiansuo Zhao, Antao Chang, Xiuchao Wang, Hongxia Sun, Xiufeng Zhang, Shengyu Yang, Chongbiao Huang, Jihui Hao,
代谢
信号转导
发育与干细胞
肿瘤
胰腺癌
干细胞
Hippo
