日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impact of community recruitment and inclusion initiatives on enrollment in the biomarker-driven MyTACTIC trial

社区招募和包容性举措对生物标志物驱动的 MyTACTIC 试验入组的影响

Zuniga, Richard M; VanderWalde, Ari; Schwartzberg, Lee S; Spigel, David R; Passler, Luke; Hong, Jason; Howland, Michael; Darbonne, Walter C; Szado, Tania; Daniel, Davey

Improved overall survival in an anti-PD-L1 treated cohort of newly diagnosed glioblastoma patients is associated with distinct immune, mutation, and gut microbiome features: a single arm prospective phase I/II trial

在接受抗PD-L1治疗的新诊断胶质母细胞瘤患者队列中,总生存期的改善与独特的免疫、突变和肠道微生物群特征相关:一项单臂前瞻性I/II期试验

Weathers, Shiao-Pei; Li, Xiqi; Zhu, Haifeng; Damania, Ashish V; Knafl, Mark; McKinley, Brian; Lin, Heather; Harrison, Rebecca A; Majd, Nazanin K; O'Brien, Barbara J; Penas-Prado, Marta; Loghin, Monica; Kamiya-Matsuoka, Carlos; Yung, W K Alfred; Solis Soto, Luisa M; Maru, Dipen M; Wistuba, Ignacio; Parra Cuentas, Edwin R; Hernandez, Sharia; Futreal, Andrew; Wargo, Jennifer A; Schulze, Katja; Darbonne, Walter C; Ajami, Nadim J; Woodman, Scott E; de Groot, John F

Neurocysticercosis of the third ventricle: illustrative case

第三脑室神经囊虫病:病例分析

Choi, John; Cullen, Grace; Darbonne, Dawn; Adams, Dennis; Coyle, Christina; Cooper, Joseph; Singh, Harminder

Assessment of Clinical Response Following Atezolizumab and Bevacizumab Treatment in Patients With Neuroendocrine Tumors: A Nonrandomized Clinical Trial

评估阿特珠单抗和贝伐珠单抗治疗神经内分泌肿瘤患者的临床反应:一项非随机临床试验

Halperin, Daniel M; Liu, Suyu; Dasari, Arvind; Fogelman, David; Bhosale, Priya; Mahvash, Armeen; Estrella, Jeannelyn S; Rubin, Laura; Morani, Ajaykumar C; Knafl, Mark; Overeem, Tim A; Fu, Szu-Chin; Solis, Luisa M; Parra Cuentas, Edwin; Verma, Anuj; Chen, Hong-Lei; Gite, Swati; Subashchandrabose, Priya; Dervin, Shannon; Schulze, Katja; Darbonne, Walter C; Yun, Cindy; Wistuba, Ignacio I; Futreal, P Andrew; Woodman, Scott E; Yao, James C

Efficacy, Safety, and Biomarker Analysis of Combined PD-L1 (Atezolizumab) and VEGF (Bevacizumab) Blockade in Advanced Malignant Peritoneal Mesothelioma

PD-L1(阿特珠单抗)和VEGF(贝伐珠单抗)联合阻断治疗晚期恶性腹膜间皮瘤的疗效、安全性和生物标志物分析

Raghav, Kanwal; Liu, Suyu; Overman, Michael J; Willett, Anneleis F; Knafl, Mark; Fu, Szu-Chin; Malpica, Anais; Prasad, Seema; Royal, Richard E; Scally, Christopher P; Mansfield, Paul F; Wistuba, Ignacio I; Futreal, Andrew P; Maru, Dipen M; Solis Soto, Luisa M; Parra Cuentas, Edwin R; Chen, Honglei; Villalobos, Pamela; Verma, Anuj; Mahvash, Armeen; Hwu, Patrick; Cortazar, Patricia; McKenna, Edward; Yun, Cindy; Dervin, Shannon; Schulze, Katja; Darbonne, Walter C; Morani, Ajaykumar C; Kopetz, Scott; Fournier, Keith F; Woodman, Scott E; Yao, James C; Varadhachary, Gauri R; Halperin, Daniel M

A Phase I Study of DLYE5953A, an Anti-LY6E Antibody Covalently Linked to Monomethyl Auristatin E, in Patients with Refractory Solid Tumors

DLYE5953A(一种与单甲基澳瑞他汀E共价连接的抗LY6E抗体)治疗难治性实体瘤患者的I期研究

Tolaney, Sara M; Do, Khanh T; Eder, Joseph P; LoRusso, Patricia M; Weekes, Colin D; Chandarlapaty, Sarat; Chang, Ching-Wei; Chen, Shang-Chiung; Nazzal, Denise; Schuth, Eva; Brunstein, Flavia; Carrasco-Triguero, Montserrat; Darbonne, Walter C; Giltnane, Jennifer M; Flanagan, William M; Commerford, S Renee; Ungewickell, Alexander; Shapiro, Geoffrey I; Modi, Shanu

Expression of MET in circulating tumor cells correlates with expression in tumor tissue from advanced-stage lung cancer patients

循环肿瘤细胞中MET的表达与晚期肺癌患者肿瘤组织中MET的表达相关

Ilie, Marius; Szafer-Glusman, Edith; Hofman, Véronique; Long-Mira, Elodie; Suttmann, Rebecca; Darbonne, Walter; Butori, Catherine; Lalvée, Salomé; Fayada, Julien; Selva, Eric; Yu, Wei; Marquette, Charles-Hugo; Shames, David S; Punnoose, Elizabeth; Hofman, Paul

Antitherapeutic antibody-mediated hepatotoxicity of recombinant human Apo2L/TRAIL in the cynomolgus monkey

抗治疗抗体介导的重组人Apo2L/TRAIL在食蟹猴中的肝毒性

Zuch de Zafra, Christina L; Ashkenazi, Avi; Darbonne, Walter C; Cheu, Melissa; Totpal, Klara; Ortega, Shirley; Flores, Heather; Walker, Mark D; Kabakoff, Bruce; Lum, Bert L; Mounho-Zamora, Barbara J; Marsters, Scot A; Dybdal, Noël O

Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells

经典的 Hedgehog 信号通路通过诱导基质血管周围细胞中 VEGF-A 的表达来增强肿瘤血管生成。

Chen, Weiwei; Tang, Tracy; Eastham-Anderson, Jeff; Dunlap, Debra; Alicke, Bruno; Nannini, Michelle; Gould, Stephen; Yauch, Robert; Modrusan, Zora; DuPree, Kelly J; Darbonne, Walter C; Plowman, Greg; de Sauvage, Frederic J; Callahan, Christopher A

Preclinical pharmacokinetics, pharmacodynamics and activity of a humanized anti-CD40 antibody (SGN-40) in rodents and non-human primates

人源化抗CD40抗体(SGN-40)在啮齿动物和非人灵长类动物中的临床前药代动力学、药效学和活性

Moser, Ann B; Hey, Jody; Dranchak, Patricia K; Karaman, Mazen W; Zhao, Junsong; Cox, Laura A; Ryder, Oliver A; Hacia, Joseph G; Karakatsani, Maria Eleni (Marilena); Samiotaki, Gesthimani; Downs, Matthew; Konofagou, Elisa; Schueler, Sherry B; Ortega, John D; Sagen, Jacqueline; Kordower, Jeffrey H; Kelley, S K; Gelzleichter, T; Xie, D; Lee, W P; Darbonne, W C; Qureshi, F; Kissler, K; Oflazoglu, E; Grewal, I S