The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma
化疗药物 CX-5461 主要针对 TOP2B,对高危神经母细胞瘤具有选择性活性
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-26640-x
Min Pan, William C Wright, Richard H Chapple, Asif Zubair, Manbir Sandhu, Jake E Batchelder, Brandt C Huddle, Jonathan Low, Kaley B Blankenship, Yingzhe Wang, Brittney Gordon, Payton Archer, Samuel W Brady, Sivaraman Natarajan, Matthew J Posgai, John Schuetz, Darcie Miller, Ravi Kalathur, Siquan Che