日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

IFNγ-associated immune-metabolic remodeling is linked to serotonin-kynurenine imbalance and cortical vulnerability in lupus-prone mice

IFNγ相关的免疫代谢重塑与易患狼疮小鼠的血清素-犬尿氨酸失衡和皮质脆弱性有关

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1740039
Matmat, Karim; Guéant-Rodriguez, Rosa-Maria; Darcq, Emmanuel; Baspinar, Okan; Alberto, Jean-Marc; Guéant, Jean-Louis; Mensah-Nyagan, Ayikoé-Guy; Jeltsch-David, Hélène
代谢
IFNγ
免疫代谢
免疫/内分泌
发表日期：2026
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Incubation of social deficit during morphine abstinence in male mice using a novel unbiased and automatized method

利用一种新型的无偏倚和自动化方法研究雄性小鼠吗啡戒断期间社交缺陷的潜伏期

期刊:Frontiers in Behavioral Neuroscience
影响因子:2.9
doi:10.3389/fnbeh.2025.1697469
Mathis, Victor P; Giua, Gabriele; Torquet, Nicolas; Mittelhaeuser, Christophe; Bour, Raphael; Kieffer, Brigitte L; Riet, Fabrice; Darcq, Emmanuel
发表日期：2025
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The GPR88 Agonist RTI-122 Reduces Alcohol-Related Motivation and Consumption

GPR88激动剂RTI-122可降低与酒精相关的动机和饮酒量

期刊:Addiction Biology
影响因子:2.6
doi:10.1111/adb.70058
Lovelock, Dennis F; Liu, Wen; Hamida, Sami Ben; Cordero, Victoria L; Van Voorhies, Kalynn J; Martin, Marion; Olmo, Isabella Guimaraes; Darcq, Emmanuel; Rahman, Md Toufiqur; Naassila, Mickael; Kieffer, Brigitte L; Jin, Chunyang; Besheer, Joyce
发表日期：2025
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Chronic Morphine Leaves a Durable Fingerprint on Whole-Brain Functional Connectivity

长期服用吗啡会在全脑功能连接上留下持久的印记

期刊:Biological Psychiatry
影响因子:9
doi:10.1016/j.biopsych.2023.12.007
Sourty, Marion; Champagnol-Di Liberti, Cédric; Nasseef, Md Taufiq; Welsch, Lola; Noblet, Vincent; Darcq, Emmanuel; Kieffer, Brigitte L
神经科学
发表日期：2024
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Mu Opioid Receptor-Expressing Neurons in the Dorsal Raphe Nucleus Are Involved in Reward Processing and Affective Behaviors

背侧缝核中表达μ阿片受体的神经元参与奖赏加工和情感行为

期刊:Biological Psychiatry
影响因子:9
doi:10.1016/j.biopsych.2023.05.019
Welsch, Lola; Colantonio, Esther; Frison, Mathilde; Johnson, Desiree A; McClain, Shannan P; Mathis, Victor; Banghart, Matthew R; Ben Hamida, Sami; Darcq, Emmanuel; Kieffer, Brigitte L
信号转导
神经科学
发表日期：2023
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Mu Opioid Receptor-Positive Neurons in the Dorsal Raphe Nucleus Are Impaired by Morphine Abstinence

吗啡戒断会损害背侧缝核中μ阿片受体阳性神经元的功能

期刊:Biological Psychiatry
影响因子:9
doi:10.1016/j.biopsych.2023.06.024
Welsch, Lola; Colantonio, Esther; Falconnier, Camille; Champagnol-DiLiberti, Cédric; Allain, Florence; Ben Hamida, Sami; Darcq, Emmanuel; Lutz, Pierre-Eric; Kieffer, Brigitte L
信号转导
神经科学
发表日期：2023
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Habenular Neurons Expressing Mu Opioid Receptors Promote Negative Affect in a Projection-Specific Manner

表达μ阿片受体的缰核神经元以投射特异性方式促进负面情绪

期刊:Biological Psychiatry
影响因子:9
doi:10.1016/j.biopsych.2022.09.013
Bailly, Julie; Allain, Florence; Schwartz, Eric; Tirel, Chloé; Dupuy, Charles; Petit, Florence; Diana, Marco A; Darcq, Emmanuel; Kieffer, Brigitte L
信号转导
神经科学
发表日期：2023
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Striatal μ-opioid receptor activation triggers direct-pathway GABAergic plasticity and induces negative affect.

纹状体α-阿片受体激活可触发直接通路GABA能可塑性，并诱发负面情绪

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2023.112089
Wang Wei, Xie Xueyi, Zhuang Xiaowen, Huang Yufei, Tan Tao, Gangal Himanshu, Huang Zhenbo, Purvines William, Wang Xuehua, Stefanov Alexander, Chen Ruifeng, Rodriggs Lucas, Chaiprasert Anita, Yu Emily, Vierkant Valerie, Hook Michelle, Huang Yun, Darcq Emmanuel, Wang Jun
信号转导
发表日期：2023
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Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation

GPR88 激动剂 RTI-13951-33 代谢稳定性的改善：设计、合成和生物学评价

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.2c01983
Md Toufiqur Rahman, Ann M Decker, Sami Ben Hamida, David A Perrey, Hetti Handi Chaminda Lakmal, Rangan Maitra, Emmanuel Darcq, Brigitte L Kieffer, Chunyang Jin
代谢
HTRF
发表日期：2023
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Advances in the characterization of negative affect caused by acute and protracted opioid withdrawal using animal models

利用动物模型对急性及长期阿片类药物戒断引起的负面情绪进行表征的研究进展

期刊:Neuropharmacology
影响因子:4.6
doi:10.1016/j.neuropharm.2023.109524
Ozdemir, Dersu; Allain, Florence; Kieffer, Brigitte L; Darcq, Emmanuel
发表日期：2023
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