日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cyclized Peptide Inhibitors of the Small G Protein Cdc42 Mimic Binding of Effector Proteins

小G蛋白Cdc42的环状肽抑制剂模拟效应蛋白的结合

Murphy, Natasha P; Tetley, George J N; Revell, Jefferson; Mott, Helen R; Owen, Darerca

ACKnowledging the role of the Activated-Cdc42 associated kinase (ACK) in regulating protein stability in cancer

认识到活化Cdc42相关激酶(ACK)在癌症中调节蛋白质稳定性的作用

Hodder, Samantha; Fox, Millie; Binti Ahmad Mokhtar, Ana Masara; Mott, Helen R; Owen, Darerca

Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK

PI3K 调节亚基核二聚体的组装受 Cdc42 激活的酪氨酸激酶 ACK 调控

Natasha S Clayton, Millie Fox, Jose J Vicenté-Garcia, Courtney M Schroeder, Trevor D Littlewood, Jonathon I Wilde, Kadalmani Krishnan, Murray J B Brown, Claire Crafter, Helen R Mott, Darerca Owen

RLIP76: A Structural and Functional Triumvirate

RLIP76:结构和功能三元组

Cornish, Jasmine; Owen, Darerca; Mott, Helen R

Progress in the therapeutic inhibition of Cdc42 signalling

Cdc42信号通路治疗抑制方面的进展

Murphy, Natasha P; Mott, Helen R; Owen, Darerca

Molecular subversion of Cdc42 signalling in cancer

癌症中Cdc42信号传导的分子调控

Murphy, Natasha P; Binti Ahmad Mokhtar, Ana Masara; Mott, Helen R; Owen, Darerca

Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases

RLIP76 Ral 结合域的亲和力成熟可为针对 Ral GTPases 的订书肽设计提供参考

Catherine A Hurd, Paul Brear, Jefferson Revell, Sarah Ross, Helen R Mott, Darerca Owen

A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases

对 RhoGDI 靶标的全面调查揭示了与非典型小 GTPase 的新型相互作用

Ana Masara Binti Ahmad Mokhtar, Samrein B M Ahmed, Nicola J Darling, Matthew Harris, Helen R Mott, Darerca Owen

Calmodulin extracts the Ras family protein RalA from lipid bilayers by engagement with two membrane-targeting motifs

钙调蛋白通过与两个膜靶向基序结合,从脂质双层中提取 Ras 家族蛋白 RalA

Samuel G Chamberlain, Andrea Gohlke, Arooj Shafiq, Iolo J Squires, Darerca Owen, Helen R Mott

Class IA PI3K regulatory subunits: p110-independent roles and structures

IA类PI3K调节亚基:p110非依赖性作用和结构

Fox, Millie; Mott, Helen R; Owen, Darerca