日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human brain organoids containing microglia that have arisen innately adapt to a β-amyloid challenge better than those in which microglia are integrated by co-culture

含有天生产生的小胶质细胞的人类脑类器官比通过共培养整合的小胶质细胞的类器官更能适应 β-淀粉样蛋白的挑战

Tyler J Wenzel, Joseph D Desjarlais, Darrell D Mousseau

Brain organoids engineered to give rise to glia and neural networks after 90 days in culture exhibit human-specific proteoforms

经过 90 天培养后,大脑类器官会形成神经胶质细胞和神经网络,并表现出人类特有的蛋白质形式

Tyler J Wenzel, Darrell D Mousseau

An (Immuno) Fluorescence Protocol for Monitoring Monoamine Oxidase A/B Protein Distribution Within the Cell

用于监测细胞内单胺氧化酶 A/B 蛋白分布的(免疫)荧光协议

Tyler J Wenzel, Jennifer N K Nyarko, Ryan M Heistad, Paul R Pennington, Chris P Phenix, Darrell D Mousseau

Detecting Monoamine Oxidase A and B Proteins: A Western Blotting Protocol and Some Practical Considerations

检测单胺氧化酶 A 和 B 蛋白:蛋白质印迹法实验方案和一些实际注意事项

Jennifer N K Nyarko, Ryan M Heistad, Paul R Pennington, Darrell D Mousseau

A Progressive Loss of phosphoSer138-Profilin Aligns with Symptomatic Course in the R6/2 Mouse Model of Huntington's Disease: Possible Sex-Dependent Signaling

磷酸化 Ser138-Profilin 的逐渐丧失与亨廷顿氏病 R6/2 小鼠模型中的症状过程一致:可能存在性别依赖性信号传导

Akanksha Baharani, Zelan Wei, William J Roesler, Darrell D Mousseau

The Aβ(1-38) peptide is a negative regulator of the Aβ(1-42) peptide implicated in Alzheimer disease progression

Aβ(1-38)肽是Aβ(1-42)肽的负调控因子,而Aβ(1-42)肽与阿尔茨海默病进展有关。

Maa O Quartey ,Jennifer N K Nyarko ,Jason M Maley ,Jocelyn R Barnes ,Maria A C Bolanos ,Ryan M Heistad ,Kaeli J Knudsen ,Paul R Pennington ,Josef Buttigieg ,Carlos E De Carvalho ,Scot C Leary ,Matthew P Parsons ,Darrell D Mousseau

Molecular characterization of an MLL1 fusion and its role in chromosomal instability

MLL1 融合的分子特征及其在染色体不稳定性中的作用

Sreejit Parameswaran, Frederick S Vizeacoumar, Kalpana Kalyanasundaram Bhanumathy, Fujun Qin, Md Fahmid Islam, Behzad M Toosi, Chelsea E Cunningham, Darrell D Mousseau, Maruti C Uppalapati, Peter C Stirling, Yuliang Wu, Keith Bonham, Andrew Freywald, Hui Li, Franco J Vizeacoumar

Female Sex Hormones and Cardiac Pressure Overload Independently Contribute to the Cardiogenic Dementia Profile in Yucatan Miniature Swine

雌性性激素和心脏压力超负荷是导致尤卡坦小型猪心源性痴呆的独立因素

Grant C Hayward, Paul J LeBlanc, Craig A Emter, Jennifer N K Nyarko, Darrell D Mousseau, Rebecca E K MacPherson, T Dylan Olver

Glycosylation States of Pre- and Post-synaptic Markers of 5-HT Neurons Differ With Sex and 5-HTTLPR Genotype in Cortical Autopsy Samples

皮质尸检样本中 5-HT 神经元突触前和突触后标记物的糖基化状态因性别和 5-HTTLPR 基因型而异

Jennifer N K Nyarko, Maa O Quartey, Ryan M Heistad, Paul R Pennington, Lisa J Poon, Kaeli J Knudsen, Odette Allonby, Amr M El Zawily, Andrew Freywald, Gail Rauw, Glen B Baker, Darrell D Mousseau

Alzheimer Disease and Selected Risk Factors Disrupt a Co-regulation of Monoamine Oxidase-A/B in the Hippocampus, but Not in the Cortex

阿尔茨海默病和某些风险因素会破坏海马体中单胺氧化酶 A/B 的共同调节,但不会破坏皮质中的单胺氧化酶

Maa O Quartey, Jennifer N K Nyarko, Paul R Pennington, Ryan M Heistad, Paula C Klassen, Glen B Baker, Darrell D Mousseau