日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV

HIV感染者CD8+ T细胞的免疫代谢缺陷会破坏肠道屏障的完整性。

Upasana Das Adhikari ,Leah M Froehle ,Alexandra N Pipkin ,Heeva Baharlou ,Alice H Linder ,Palak Shah ,Amanda Hussey ,Qiming Zhang ,Sarah Nyquist ,Saleh Khwaled ,Fangtao Chi ,Swagata Goswami ,Sabhyata Sedhain ,Salina Hussain ,Thomas J Diefenbach ,Benjamin J Read ,Byungji Kim ,Darrell Irvine ,Osaretin Asowata ,Mark Ladinsky ,Pamela Bjorkman ,Fusi Madela ,Shakeel Kader ,Alex K Shalek ,Musie Ghebremichael ,Henrik Kloverpris ,Alison E Ringel ,Ömer H Yilmaz ,Douglas S Kwon

Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity

在没有多反应性的情况下产生针对 HIV-1 gp41 膜近端外部区域特异性分泌抗体的长寿骨髓浆细胞

Luke R Donius, Yuxing Cheng, Jaewon Choi, Zhen-Yu J Sun, Melissa Hanson, Michael Zhang, Todd M Gierahn, Susanna Marquez, Mohammed Uduman, Steven H Kleinstein, Darrell Irvine, J Christopher Love, Ellis L Reinherz, Mikyung Kim

Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry

膜结合 HIV-1 gp41 膜近端外部区域 (MPER) 片段的免疫原性主要受残基可及性控制,并受立体化学调节

Mikyung Kim, Likai Song, James Moon, Zhen-Yu J Sun, Anna Bershteyn, Melissa Hanson, Derek Cain, Selasie Goka, Garnett Kelsoe, Gerhard Wagner, Darrell Irvine, Ellis L Reinherz