日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Preferential remdesivir triphosphate incorporation by SARS-CoV-2 polymerase is altered to ATP by the S759A mutation

SARS-CoV-2 聚合酶优先掺入瑞德西韦三磷酸盐的机制，因 S759A 突变而改变为 ATP。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-026-09844-z
Gordon, Calvin J; Oliva, Mizar F; Lee, Hery W; Goovaerts, Quinten; De Wijngaert, Brent; Götte, Matthias; Das, Kalyan
SARS-CoV-2
发表日期：2026
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Efficacy and safety of semaglutide injection in comparison with reference semaglutide for chronic weight management in indian adults with obesity: A phase III randomized non-inferiority trial

一项III期随机非劣效性试验，比较注射用索玛鲁肽与参考药物索玛鲁肽在印度肥胖成人慢性体重管理中的疗效和安全性

期刊:Metabolism Open
影响因子:2.7
doi:10.1016/j.metop.2026.100460
Sharma, Prabhat Kumar; Redkar, Sagar Vivek; Madhav Karmalkar, Abhishek; Anand, Sumit; Patil, Vijaykumar Shivajirao; Nurulhasan, Ansari Rizwanahmed; Manan Bharatkumar, Patel; Barge, Vijaykumar; Shah, Shalin J; Patel, Chintan B; Choudhary, Animesh; Sudheer, Kanugula; Rambabu, Konatham; Narasinga Rao, S; Swapna, M; Ankathi, Shravan Kumar; Singh, Veer Bahadur; Sarkar, Gouranga; Gautam, S K; Das, Kalyan Kumar; Bhattacharya, Raja; Tripathi, Kaushalendra Nath; Sudarsi, Budithi; Parmar, Deven; Kansagra, Kevin; Pathak, Hardik
肥胖
代谢
发表日期：2026
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Protocol to investigate human mitochondrial transcription initiation by integrating biochemical and cryo-EM approaches.

通过整合生物化学和冷冻电镜方法研究人类线粒体转录起始的方案。

期刊:STAR Protocols
影响因子:1.3
doi:10.1016/j.xpro.2025.104347
Ajjugal Yogeeshwar, Goovaerts Quinten, Shen Jiayu, De Wijngaert Brent, Das Kalyan, Patel Smita S
线粒体
发表日期：2026
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Inhibitory effects of molnupiravir on Crimean-Congo hemorrhagic fever virus polymerase.

莫努匹拉韦对克里米亚-刚果出血热病毒聚合酶的抑制作用。

期刊:
影响因子:
doi:10.1093/narmme/ugaf041
Sloan Angela, Gordon Calvin J, Prévost Jérémie, Audet Jonathan, Fulton Kathleen, Woolner Emma, Chang Ming-Hao, Walker Simon M, Tchesnokov Egor P, Das Kalyan, Safronetz David, Götte Matthias
微生物学
出血热
发表日期：2026
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Structural insights into transcription regulation of the global OmpR/PhoB family regulator PhoP from Mycobacterium tuberculosis

结核分枝杆菌中全局 OmpR/PhoB 家族调控因子 PhoP 转录调控的结构解析

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-56697-x
Shi, Jing; Feng, Zhenzhen; Song, Qian; Wen, Aijia; Liu, Tianyu; Xu, Liqiao; Ye, Zonghang; Xu, Simin; Gao, Fei; Xiao, Liuxiang; Zhu, Jiapeng; Das, Kalyan; Zhao, Guoping; Li, Jie; Feng, Yu; Lin, Wei
信号转导
表观遗传
转录调控
发表日期：2025
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A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses

一种基于胍的冠状病毒复制抑制剂，靶向nsp15核糖核酸内切酶，并筛选出对干扰素敏感的突变病毒。

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1012571
Van Loy, Benjamin; Pujol, Eugènia; Kamata, Kenichi; Lee, Xiao Yin; Bakirtzoglou, Nikolai; Van Berwaer, Ria; Vandeput, Julie; Mestdagh, Cato; Persoons, Leentje; De Wijngaert, Brent; Goovaerts, Quinten; Noppen, Sam; Jacquemyn, Maarten; Ahmadzadeh, Kourosh; Bernaerts, Eline; Martín-López, Juan; Escriche, Celia; Vanmechelen, Bert; Krasniqi, Besir; Singh, Abhimanyu K; Daelemans, Dirk; Maes, Piet; Matthys, Patrick; Dehaen, Wim; Rozenski, Jef; Das, Kalyan; Voet, Arnout; Vázquez, Santiago; Naesens, Lieve; Stevaert, Annelies
微生物学
发表日期：2025
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Structural basis for selective remdesivir incorporation by SARS-CoV-2 RNA polymerase, and S759A resistance

SARS-CoV-2 RNA聚合酶选择性掺入瑞德西韦的结构基础及S759A耐药性

期刊:
影响因子:
doi:10.1101/2025.09.04.674295
Gordon, Calvin J; Oliva, Mizar F; Lee, Hery W; Goovaerts, Quinten; De Wijngaert, Brent; Götte, Matthias; Das, Kalyan
SARS-CoV-2
发表日期：2025
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Structural basis for selective remdesivir incorporation by SARS-CoV-2 polymerase, and S759A resistance

SARS-CoV-2聚合酶选择性掺入瑞德西韦的结构基础及S759A耐药性

期刊:
影响因子:
doi:10.21203/rs.3.rs-7793649/v1
Das, Kalyan; Gordon, Calvin; Oliva, Mizar; Lee, Hery; Goovaerts, Quinten; De Wijngaert, Brent; Gotte, Matthias
SARS-CoV-2
发表日期：2025
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Structural and functional insights into transcription activation of the essential LysR-type transcriptional regulators

对必需的LysR型转录调控因子的转录激活的结构和功能见解

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.5012
Shi, Jing; Feng, Zhenzhen; Song, Qian; Wang, Fulin; Zhang, Zhipeng; Liu, Jian; Li, Fangfang; Wen, Aijia; Liu, Tianyu; Ye, Zonghang; Zhang, Chao; Das, Kalyan; Wang, Shuang; Feng, Yu; Lin, Wei
信号转导
表观遗传
转录调控
发表日期：2024
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Combination of ganciclovir and trifluridine prevents drug-resistance emergence in HSV-1

更昔洛韦和三氟尿苷联合用药可预防HSV-1产生耐药性。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00110-24
Schalkwijk, Hanna Helena; Shewakramani, Neesha Rajesh; Das, Kalyan; Andrei, Graciela; Snoeck, Robert
发表日期：2024
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