日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dynamic Supercoiling Sponsors Transcription Amplification by MYC

动态超螺旋通过 MYC 促进转录扩增

Jha, Rajiv Kumar; Kouzine, Fedor; Wang, Bo; Phelan, James D; Das, Subhendu K; Lewis, Brian A; Levens, David

A tumorigenesis threshold for endogenous Myc revealed by dosage-compensation for Myc-haploinsufficiency in the absence of p53.

在缺乏 p53 的情况下,通过 Myc 单倍体不足的剂量补偿,揭示了内源性 Myc 的致瘤阈值。

Bao Xiaozhong, Abdullaev Zied, Das Subhendu K, Zgonc Valerie, Ylaya Kris, Pittaluga Stefania, Hewitt Stephen M, Sedivy John M, Pack Svetlana J, Mackem Susan, Levens David

Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome.

MYC拓扑体活性过高会引发急性DNA损伤、MYC降解,并被p53拓扑体取代

Das Subhendu K, Karmakar Sharmistha, Venkatachalapathy Harish, Jha Rajiv Kumar, Batchelor Eric, Levens David

MYC: a complex problem

MYC:一个复杂的问题

Das, Subhendu K; Lewis, Brian A; Levens, David