A tumorigenesis threshold for endogenous Myc revealed by dosage-compensation for Myc-haploinsufficiency in the absence of p53.
在缺乏 p53 的情况下,通过 Myc 单倍体不足的剂量补偿,揭示了内源性 Myc 的致瘤阈值。
期刊:
影响因子:
doi:10.1101/2025.07.28.667174
Bao Xiaozhong, Abdullaev Zied, Das Subhendu K, Zgonc Valerie, Ylaya Kris, Pittaluga Stefania, Hewitt Stephen M, Sedivy John M, Pack Svetlana J, Mackem Susan, Levens David