The low endoribonuclease activity and lack of rNMP preference of human mitochondrial topoisomerase 1 protect against ribonucleotide-dependent deletions.
人类线粒体拓扑异构酶 1 的核糖核酸内切酶活性低且缺乏 rNMP 偏好性,可防止核糖核苷酸依赖性缺失
期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf475
Bader Cyrielle P J, Miyazaki-Kasho Erika, Forslund Josefin M E, Dash Aiswarya, Wessels Malgorzata, Wanrooij Paulina H