日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model

突变型IDH2的小分子抑制剂可挽救D-2-羟基戊二酸尿症II型小鼠模型的心肌病

Wang, Fang; Travins, Jeremy; Lin, Zhizhong; Si, Yaguang; Chen, Yue; Powe, Josh; Murray, Stuart; Zhu, Dongwei; Artin, Erin; Gross, Stefan; Santiago, Stephanie; Steadman, Mya; Kernytsky, Andrew; Straley, Kimberly; Lu, Chenming; Pop, Ana; Struys, Eduard A; Jansen, Erwin E W; Salomons, Gajja S; David, Muriel D; Quivoron, Cyril; Penard-Lacronique, Virginie; Regan, Karen S; Liu, Wei; Dang, Lenny; Yang, Hua; Silverman, Lee; Agresta, Samuel; Dorsch, Marion; Biller, Scott; Yen, Katharine; Cang, Yong; Su, Shin-San Michael; Jin, Shengfang

Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs

caprin-1 的独特结构特征介导其与 G3BP-1 的相互作用,并诱导真核翻译起始因子 2α 的磷酸化、进入细胞质应激颗粒以及与部分 mRNA 的选择性相互作用。

Solomon, Samuel; Xu, Yaoxian; Wang, Bin; David, Muriel D; Schubert, Peter; Kennedy, Derek; Schrader, John W

Epigenetic control of the immune escape mechanisms in malignant carcinomas

恶性肿瘤免疫逃逸机制的表观遗传调控

Setiadi, A Francesca; David, Muriel D; Seipp, Robyn P; Hartikainen, Jennifer A; Gopaul, Rayshad; Jefferies, Wilfred A

Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen.

不同的机制决定了生长因子或抗原受体对 H-Ras、N-Ras、K-Ras 4B 和 M-Ras 的差异性激活模式

Ehrhardt Annette, David Muriel D, Ehrhardt Götz R A, Schrader John W