日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The schedule of ATR inhibitor AZD6738 can potentiate or abolish antitumor immune responses to radiotherapy

ATR 抑制剂 AZD6738 的给药方案可以增强或消除放射治疗的抗肿瘤免疫反应

Frank P Vendetti, Pinakin Pandya, David A Clump, Sandra Schamus-Haynes, Meysam Tavakoli, Maria diMayorca, Naveed M Islam, Jina Chang, Greg M Delgoffe, Jan H Beumer, Christopher J Bakkenist

Dose-dependent bioavailability, absorption-rate limited elimination, and tissue distribution of the ATR inhibitor BAY-1895344 (elimusertib) in mice

ATR 抑制剂 BAY-1895344 (elimusertib) 在小鼠体内的剂量依赖性生物利用度、吸收速率受限消除和组织分布

Brian F Kiesel, Joshua J Deppas, Jianxia Guo, Robert A Parise, David A Clump, Christopher J Bakkenist, Jan H Beumer

Dose-dependent bioavailability and tissue distribution of the ATR inhibitor AZD6738 (ceralasertib) in mice

ATR 抑制剂 AZD6738 (ceralasertib) 在小鼠体内的剂量依赖性生物利用度和组织分布

Brian F Kiesel, Jianxia Guo, Robert A Parise, Raman Venkataramanan, David A Clump, Christopher J Bakkenist, Jan H Beumer

Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints

通过废除细胞周期检查点来靶向头颈癌中的 DNA 损伤反应

Jessica M Molkentine, David P Molkentine, Kathleen A Bridges, Tongxin Xie, Liangpeng Yang, Aakash Sheth, Timothy P Heffernan, David A Clump, Alma Z Faust, Robert L Ferris, Jeffrey N Myers, Mitchell J Frederick, Kathryn A Mason, Raymond E Meyn, Curtis R Pickering, Heath D Skinner

Circulating exosomes measure responses to therapy in head and neck cancer patients treated with cetuximab, ipilimumab, and IMRT

循环外泌体测量接受西妥昔单抗、伊匹单抗和 IMRT 治疗的头颈癌患者的治疗反应

Marie-Nicole Theodoraki, Saigopalakrishna Yerneni, William E Gooding, James Ohr, David A Clump, Julie E Bauman, Robert L Ferris, Theresa L Whiteside

PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer

CD8+ T 细胞中的 PD-1 状态与头颈癌的生存和抗 PD-1 治疗结果相关

Benjamin A Kansy, Fernando Concha-Benavente, Raghvendra M Srivastava, Hyun-Bae Jie, Gulidanna Shayan, Yu Lei, Jessica Moskovitz, Jennifer Moy, Jing Li, Sven Brandau, Stephan Lang, Nicole C Schmitt, Gordon J Freeman, William E Gooding, David A Clump, Robert L Ferris

Preclinical immunoPET/CT imaging using Zr-89-labeled anti-PD-L1 monoclonal antibody for assessing radiation-induced PD-L1 upregulation in head and neck cancer and melanoma

使用 Zr-89 标记的抗 PD-L1 单克隆抗体进行临床前免疫 PET/CT 成像,以评估头颈癌和黑色素瘤中放射诱导的 PD-L1 上调

Masahiro Kikuchi, David A Clump, Raghvendra M Srivastava, Lingyi Sun, Dexing Zeng, Julio A Diaz-Perez, Carolyn J Anderson, W Barry Edwards, Robert L Ferris