日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduced response to SARS-CoV-2 vaccination is associated with impaired immunoglobulin class switch recombination in SLE patients

SARS-CoV-2 疫苗接种反应降低与 SLE 患者免疫球蛋白类别转换重组受损有关

Guillem Montamat, Claire E Meehan, Hannah F Bradford, Reşit Yıldırım, Francisca Guimarães, Marina Johnson, David Goldblatt, David A Isenberg, Claudia Mauri

Thioredoxin is a metabolic rheostat controlling regulatory B cells

硫氧还蛋白是一种代谢调节器,控制着调节性B细胞。

Hannah F Bradford ,Thomas C R McDonnell ,Alexander Stewart ,Andrew Skelton ,Joseph Ng ,Zara Baig ,Franca Fraternali ,Deborah Dunn-Walters ,David A Isenberg ,Adnan R Khan ,Claudio Mauro ,Claudia Mauri

Inactive disease in patients with lupus is linked to autoantibodies to type I interferons that normalize blood IFNα and B cell subsets

红斑狼疮患者的非活动期疾病与针对 I 型干扰素的自身抗体有关,这些自身抗体可使血液中的 IFNα 和 B 细胞亚群恢复正常。

Hannah F Bradford ,Liis Haljasmägi ,Madhvi Menon ,Thomas C R McDonnell ,Karita Särekannu ,Martti Vanker ,Pärt Peterson ,Chris Wincup ,Rym Abida ,Raquel Fernandez Gonzalez ,Vincent Bondet ,Darragh Duffy ,David A Isenberg ,Kai Kisand ,Claudia Mauri

Identification of biomarkers to stratify response to B-cell-targeted therapies in systemic lupus erythematosus: an exploratory analysis of a randomised controlled trial

识别生物标志物以分层系统性红斑狼疮对 B 细胞靶向治疗的反应:一项随机对照试验的探索性分析

Muhammad Shipa, Liliana R Santos, Dao X Nguyen, Andrew Embleton-Thirsk, Mariea Parvaz, Lauren L Heptinstall, Ruth J Pepper, David A Isenberg, Caroline Gordon, Michael R Ehrenstein

Disparity in peripheral and renal B-cell depletion with rituximab in systemic lupus erythematosus: an opportunity for obinutuzumab?

系统性红斑狼疮中利妥昔单抗导致外周和肾脏 B 细胞耗竭的差异:奥滨尤妥珠单抗的机会?

Venkat R Reddy, Ruth J Pepper, Kavina Shah, Geraldine Cambridge, Scott R Henderson, Christian Klein, Loren Kell, Samuel J Taylor, David A Isenberg, Mark S Cragg, Maria J Leandro

Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE

载脂蛋白B/A1比值升高可预测青少年发病型系统性红斑狼疮患者的心血管代谢风险。

George A Robinson ,Kirsty E Waddington ,Leda Coelewij ,Junjie Peng ,Meena Naja ,Chris Wincup ,Anna Radziszewska ,Hannah Peckham ,David A Isenberg ,Yiannis Ioannou ,Coziana Ciurtin ,Ines Pineda-Torra ,Elizabeth C Jury

CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes

CD5 表达通过激活 MAPK/Erk 通路和上调 B 淋巴细胞中的 TRPC1 通道来促进 IL-10 的产生

Soizic Garaud, Taher E Taher, Marjolaine Debant, Miguel Burgos, Sarra Melayah, Christian Berthou, Kaushal Parikh, Jacques-Olivier Pers, Damien Luque-Paz, Gilles Chiocchia, Maikel Peppelenbosch, David A Isenberg, Pierre Youinou, Olivier Mignen, Yves Renaudineau, Rizgar A Mageed

Gene expression profiling identifies distinct molecular signatures in thrombotic and obstetric antiphospholipid syndrome

基因表达谱鉴定了血栓和产科抗磷脂综合征中的不同分子特征

Vera M Ripoll, Francesca Pregnolato, Simona Mazza, Caterina Bodio, Claudia Grossi, Thomas McDonnell, Charis Pericleous, Pier Luigi Meroni, David A Isenberg, Anisur Rahman, Ian P Giles

CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α

CD19+CD24hiCD38hi B 细胞在青少年皮肌炎中扩增,并在通过 Toll 样受体 7 和干扰素-α 激活后表现出促炎表型

Christopher J M Piper, Meredyth G Ll Wilkinson, Claire T Deakin, Georg W Otto, Stefanie Dowle, Chantal L Duurland, Stuart Adams, Emiliano Marasco, Elizabeth C Rosser, Anna Radziszewska, Rita Carsetti, Yiannis Ioannou, Philip L Beales, Daniel Kelberman, David A Isenberg, Claudia Mauri, Kiran Nistala,

Low Percentage of Signal Regulatory Protein α/β+ Memory B Cells in Blood Predicts Development of Anti-drug Antibodies (ADA) in Adalimumab-Treated Rheumatoid Arthritis Patients

血液中信号调节蛋白α/β+记忆B细胞比例低可预测接受阿达木单抗治疗的类风湿性关节炎患者体内抗药抗体(ADA)的产生

Laura Magill ,Marsilio Adriani ,Véronique Berthou ,Keguan Chen ,Aude Gleizes ,Salima Hacein-Bey-Abina ,Agnes Hincelin-Mery ,Xavier Mariette ,Marc Pallardy ,Sebastian Spindeldreher ,Natacha Szely ,David A Isenberg ,Jessica J Manson ,Elizabeth C Jury ,Claudia Mauri