日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolic engineering to facilitate anti-tumor immunity

利用代谢工程促进抗肿瘤免疫

Tanya Schild,Patrick Wallisch,Yixuan Zhao,Ya-Ting Wang,Lyric Haughton,Rachel Chirayil,Kaitlyn Pierpont,Kevin Chen,Sara Nunes-Violante,Justin Cross,Elisa de Stanchina,Craig B Thompson,David A Scheinberg,Justin S A Perry,Kayvan R Keshari  0

Metabolic engineering to facilitate anti-tumor immunity

利用代谢工程促进抗肿瘤免疫

Tanya Schild ,Patrick Wallisch ,Yixuan Zhao ,Ya-Ting Wang ,Lyric Haughton ,Rachel Chirayil ,Kaitlyn Pierpont ,Kevin Chen ,Sara Nunes-Violante ,Justin Cross ,Elisa de Stanchina ,Craig B Thompson ,David A Scheinberg ,Justin S A Perry ,Kayvan R Keshari

CD8 co-receptor modulates the specificity profile of the 1G4 TCR against NY-ESO-1

CD8 共受体调节 1G4 TCR 对 NY-ESO-1 的特异性谱

Heather F Jones ,Zita E H Aretz ,Ron S Gejman ,Tara Cicic ,David A Scheinberg

Microenvironment actuated CAR T cells improve solid tumor efficacy without toxicity

微环境激活的CAR-T细胞可提高实体瘤疗效且无毒性

Kristen C Vogt,Pedro C Silberman,Qianqian Lin,James E Han,Amy Laflin,Hendryck A Gellineau,Daniel A Heller,David A Scheinberg

Wilms' tumor 1 (WT1) antigen is overexpressed in Kaposi Sarcoma and is regulated by KSHV vFLIP

Wilms肿瘤1(WT1)抗原在卡波西肉瘤中过度表达,并受KSHV vFLIP调控。

Ayana E Morales ,Ruby Gumenick ,Caitlyn M Genovese ,Yun Yeong Jang ,Ariene Ouedraogo ,Maite Ibáñez de Garayo ,Tania Pannellini ,Sanjay Patel ,Matthew E Bott ,Julio Alvarez ,Sung Soo Mun ,Jennifer Totonchy ,Archana Gautam ,Jesus Delgado de la Mora ,Stephanie Chang ,Dagmar Wirth ,Marcelo Horenstein ,Tao Dao ,David A Scheinberg ,Paul G Rubinstein ,Aggrey Semeere ,Jeffrey Martin ,Catherine C Godfrey ,Carlee B Moser ,Roy M Matining ,Thomas B Campbell ,Margaret Z Borok ,Susan E Krown ,Ethel Cesarman

Potentiating antibody-dependent killing of cancers with CAR T cells secreting CD47-SIRPα checkpoint blocker

利用分泌 CD47-SIRPα 检查点阻断剂的 CAR-T 细胞增强抗体依赖性癌症杀伤力

Megan M Dacek, Keifer G Kurtz, Patrick Wallisch, Stephanie A Pierre, Shireen Khayat, Christopher M Bourne, Thomas J Gardner, Kristen C Vogt, Nica Aquino, Anas Younes, David A Scheinberg

Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications

工程改造 CAR-T 细胞用于成像和放射免疫治疗中的放射性半抗原捕获

Keifer Kurtz,Laura Eibler,Megan M Dacek,Lukas M Carter,Darren R Veach,Samantha Lovibond,Emma Reynaud,Sarah Qureshy,Michael R McDevitt,Christopher Bourne,Sebastien Monette,Blesida Punzalan,Shireen Khayat,Svena Verma,Adam L Kesner,Nai-Kong V Cheung,Heiko Schöder,Leah Gajecki,Sarah M Cheal,Steven M Larson,David A Scheinberg,Simone Krebs

The landscape of MHC-presented phosphopeptides yields actionable shared tumor antigens for cancer immunotherapy across multiple HLA alleles

MHC 呈递磷酸肽的概况为跨多个 HLA 等位基因的癌症免疫治疗提供了可操作的共享肿瘤抗原

Zaki Molvi, Martin G Klatt, Tao Dao, Jessica Urraca, David A Scheinberg, Richard J O'Reilly

Dual targeting ovarian cancer by Muc16 CAR T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1

Muc16 CAR-T 细胞分泌针对细胞内肿瘤抗原 WT1 的双特异性 T 细胞接合抗体,双重靶向卵巢癌

Sung Soo Mun, Jeremy Meyerberg, Leila Peraro, Tatyana Korontsvit, Thomas Gardner, Manish Malviya, Chrisann Kyi, Roisin E O'Cearbhaill, Cheng Liu, Tao Dao, David A Scheinberg

Host Interactions with Engineered T-cell Micropharmacies

宿主与工程化T细胞微药房的相互作用

Christopher M Bourne ,Patrick Wallisch ,Megan M Dacek ,Thomas J Gardner ,Stephanie Pierre ,Kristen Vogt ,Broderick C Corless ,Mamadou A Bah ,Jesus E Romero-Pichardo ,Angel Charles ,Keifer G Kurtz ,Derek S Tan ,David A Scheinberg