Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits
一项针对临床定义的尼古丁依赖的多祖先全基因组关联研究揭示了其与其他物质使用障碍和健康相关性状的强遗传关联。
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doi:10.1101/2025.01.29.25320962
Johnson, Emma C; Lai, Dongbing; Miller, Alex P; Hatoum, Alexander S; Deak, Joseph D; Balbona, Jared V; Baranger, David Aa; Galimberti, Marco; Sanichwankul, Kittipong; Thorgeirsson, Thorgeir; Colbert, Sarah Mc; Sanchez-Roige, Sandra; Adhikari, Keyrun; Docherty, Anna; Degenhardt, Louisa; Edwards, Tobias; Fox, Louis; Giannelis, Alexandros; Jeffries, Paul; Korhonen, Tellervo; Morrison, Claire; Nunez, Yaira Z; Palviainen, Teemu; Su, Mei-Hsin; Villela, Pamela N Romero; Wetherill, Leah; Willoughby, Emily A; Zellers, Stephanie; Bierut, Laura; Buchwald, Jadwiga; Copeland, William; Corley, Robin; Friedman, Naomi P; Foroud, Tatiana M; Gillespie, Nathan A; Gizer, Ian R; Heath, Andrew C; Hickie, Ian B; Kaprio, Jaakko A; Keller, Matthew C; Lee, James L; Lind, Penelope A; Madden, Pamela A; Maes, Hermine Hm; Martin, Nicholas G; McGue, Matt; Medland, Sarah E; Nelson, Elliot C; Pearson, John V; Porjesz, Bernice; Stallings, Michael; Vrieze, Scott; Wilhelmsen, Kirk C; Walters, Raymond K; Polimanti, Renato; Malison, Robert T; Zhou, Hang; Stefansson, Kari; Potenza, Marc N; Mutirangura, Apiwat; Shotelersuk, Vorasuk; Kalayasiri, Rasmon; Edenberg, Howard J; Gelernter, Joel; Agrawal, Arpana
