日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dose escalation pre-clinical trial of novel DOK7-AAV in mouse model of DOK7 congenital myasthenia

新型 DOK7-AAV 在 DOK7 先天性肌无力小鼠模型中的剂量递增临床前试验

Judith Cossins, Imre Kozma, Claudia Canzonetta, Al Hawkins, David Beeson, Patricio Sepulveda, Yin Yao Dong

Frequency of and sex distribution in specific phobia subtypes in a treatment-seeking sample

在寻求治疗的样本中,特定恐惧症亚型的发生频率和性别分布

Veale, David; Beeson, Charles; Papageorgiou, Andriani

Unraveling the molecular interactions between α7 nicotinic receptor and a RIC3 variant associated with backward speech

揭示 α7 烟碱受体与与倒退言语相关的 RIC3 变体之间的分子相互作用

Aditi Pradhan, Hayley Mounford, Jessica Peixinho, Edward Rea, Emmanouela Epeslidou, Julia S Scott, Joanna Cull, Susan Maxwell, Richard Webster, David Beeson, Yin Yao Dong, Stefan Prekovic, Isabel Bermudez, Dianne F Newbury

IgG1-3 MuSK Antibodies Inhibit AChR Cluster Formation, Restored by SHP2 Inhibitor, Despite Normal MuSK, DOK7, or AChR Subunit Phosphorylation

IgG1-3 MuSK 抗体可抑制 AChR 簇形成,而 SHP2 抑制剂可恢复该簇形成,尽管 MuSK、DOK7 或 AChR 亚基磷酸化处于正常状态

Michelangelo Cao, Wei-Wei Liu, Susan Maxwell, Saif Huda, Richard Webster, Amelia Evoli, David Beeson, Judith A Cossins, Angela Vincent

Myasthenia gravis AChR antibodies inhibit function of rapsyn-clustered AChRs

重症肌无力 AChR 抗体抑制 rapsyn 聚集 AChR 的功能

Hakan Cetin, Richard Webster, Wei Wei Liu, Akiko Nagaishi, Inga Koneczny, Fritz Zimprich, Susan Maxwell, Judith Cossins, David Beeson, Angela Vincent

Congenital myasthenic syndrome due to mutations in MUSK suggests that the level of MuSK phosphorylation is crucial for governing synaptic structure

先天性肌无力综合征是由MUSK基因突变引起的,这表明MuSK磷酸化水平对于调控突触结构至关重要。

Pedro M Rodríguez Cruz ,Judith Cossins ,Jonathan Cheung ,Susan Maxwell ,Sandeep Jayawant ,Ruth Herbst ,Dominic Waithe ,Alexandr P Kornev ,Jacqueline Palace ,David Beeson

β2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure

β2-肾上腺素受体激动剂可改善长期服用吡啶斯的明对神经肌肉接头结构的不良影响

An E Vanhaesebrouck, Richard Webster, Susan Maxwell, Pedro M Rodriguez Cruz, Judith Cossins, James Wickens, Wei-Wei Liu, Hakan Cetin, Jonathan Cheung, Hayley Ramjattan, Jacqueline Palace, David Beeson

RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: a case-control study

RTS,S/AS01E 免疫接种可增强非洲儿童对疫苗无关的恶性疟原虫抗原的抗体反应,从而增强其对临床疟疾的保护作用:一项病例对照研究

Dobaño, Carlota; Ubillos, Itziar; Jairoce, Chenjerai; Gyan, Ben; Vidal, Marta; Jiménez, Alfons; Santano, Rebeca; Dosoo, David; Nhabomba, Augusto J; Ayestaran, Aintzane; Aguilar, Ruth; Williams, Nana Aba; Díez-Padrisa, Núria; Lanar, David; Chauhan, Virander; Chitnis, Chetan; Dutta, Sheetij; Gaur, Deepak; Angov, Evelina; Asante, Kwaku Poku; Owusu-Agyei, Seth; Valim, Clarissa; Gamain, Benoit; Coppel, Ross L; Cavanagh, David; Beeson, James G; Campo, Joseph J; Moncunill, Gemma

SHP2 inhibitor protects AChRs from effects of myasthenia gravis MuSK antibody

SHP2 抑制剂保护 AChR 免受重症肌无力 MuSK 抗体的影响

Saif Huda, Michelangelo Cao, Anna De Rosa, Mark Woodhall, Pedro M Rodriguez Cruz, Judith Cossins, Michelangelo Maestri, Roberta Ricciardi, Amelia Evoli, David Beeson, Angela Vincent

Characterization of pathogenic monoclonal autoantibodies derived from muscle-specific kinase myasthenia gravis patients

源自肌肉特异性激酶重症肌无力患者的致病性单克隆自身抗体的表征

Kazushiro Takata, Panos Stathopoulos, Michelangelo Cao, Marina Mané-Damas, Miriam L Fichtner, Erik S Benotti, Leslie Jacobson, Patrick Waters, Sarosh R Irani, Pilar Martinez-Martinez, David Beeson, Mario Losen, Angela Vincent, Richard J Nowak, Kevin C O'Connor