日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice

小鼠小胶质细胞中与 ALS/FTD 相关的 TBK1 缺陷会诱导类似衰老的小胶质细胞特征,并导致小鼠社交识别缺陷。

Isadora Lenoel,Matthieu Ribon,Félicie Lorenc,Aurélien Diebold,Clementine E Philibert,David Robaldo,Manel Badsi,Julianne Perronnet,Julie Lameth,Felix Berriat,Hidemi Misawa,Marie Coutelier,Raphaelle Cassel,Nadège Sarrazin,Coline Jost-Mousseau,Delphine Bohl,Stéphanie Millecamps,Michel Mallat,David Brenner,Jochen H Weishaupt,Séverine Boillée,Christian S Lobsiger

Cell type mapping of inflammatory muscle diseases highlights selective myofiber vulnerability in inclusion body myositis

炎症性肌肉疾病的细胞类型定位突显了包涵体肌炎中肌纤维的选择性脆弱性

Sven Wischnewski # ,Thomas Thäwel # ,Chiseko Ikenaga # ,Anna Kocharyan # ,Celia Lerma-Martin ,Amel Zulji ,Hans-Werner Rausch ,David Brenner ,Leonie Thomas ,Michael Kutza ,Brittney Wick ,Tim Trobisch ,Corinna Preusse ,Maximilian Haeussler ,Jan Leipe ,Albert Ludolph ,Angela Rosenbohm ,Ahmet Hoke ,Michael Platten ,Jochen H Weishaupt ,Clemens J Sommer ,Werner Stenzel ,Thomas E Lloyd ,Lucas Schirmer

A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice

TBK1 变体导致小鼠自噬溶酶体和运动神经元病理,但不会引起神经炎症

David Brenner #, Kirsten Sieverding #, Jahnavi Srinidhi, Susanne Zellner, Christopher Secker, Rüstem Yilmaz, Julia Dyckow, Shady Amr, Anna Ponomarenko, Esra Tunaboylu, Yasmin Douahem, Joana S Schlag, Lucía Rodríguez Martínez, Georg Kislinger, Cornelia Niemann, Karsten Nalbach, Wolfgang P Ruf, Jonath

Heterozygous knockout of Synaptotagmin13 phenocopies ALS features and TP53 activation in human motor neurons

Synaptotagmin13 杂合敲除表型模拟了人类运动神经元中的 ALS 特征和 TP53 激活

Johannes Lehmann #, Amr Aly #, Christina Steffke, Luca Fabbio, Valentin Mayer, Natalie Dikwella, Kareen Halablab, Francesco Roselli, Simone Seiffert, Tobias M Boeckers, David Brenner, Edor Kabashi, Medhanie Mulaw, Ritchie Ho, Alberto Catanese

Intrahepatic neutrophil accumulation and extracellular trap formation are associated with posthepatectomy liver failure

肝内中性粒细胞聚集和细胞外陷阱形成与肝切除术后肝功能衰竭相关。

Brunnthaler, Laura; Pereyra, David; Brenner, Miriam; Santol, Jonas; Herrmann, Lukas; Schrottmaier, Waltraud C; Pirabe, Anita; Schmuckenschlager, Anna; Kim, Sarang; Kern, Anna Emilia; Huber, Felix Xaver; Michels, Lisa Emilie; Brostjan, Christine; Salzmann, Manuel; Hohensinner, Philipp; Kain, Renate; Gruenberger, Thomas; Starlinger, Patrick; Assinger, Alice

Methods matter: Exploring how expectations influence common actions

方法很重要:探究期望如何影响常见行为

Ghiani, Andrea; Mann, David; Brenner, Eli

Tracheostomy-related durable medical equipment: Insurance coverage, gaps, and barriers

气管切开术相关耐用医疗设备:保险覆盖范围、缺口和障碍

Foran, Palmer L; Benjamin, William J 4th; Sperry, Ethan D; Best, Simon R; Boisen, Sarah E; Bosworth, Barbara; Brodsky, Martin B; Shaye, David; Brenner, Michael J; Pandian, Vinciya

A systematic review of suicidal ideation and behaviors among adults with spinal cord injury

对脊髓损伤成年人自杀意念和行为的系统性综述

Betthauser, Lisa M; Hoffberg, Adam S; Stearns-Yoder, Kelly A; Harmon, Matthew; Coons, David; Brenner, Lisa A

Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice

Tbk1 半合子缺失使 TDP-43G298S 转基因小鼠的神经肌肉接头病理恶化

Kirsten Sieverding, Johannes Ulmer, Clara Bruno, Takashi Satoh, William Tsao, Axel Freischmidt, Shizuo Akira, Philip C Wong, Albert C Ludolph, Karin M Danzer, Christian S Lobsiger, David Brenner, Jochen H Weishaupt

Exposure of Human Skin Models to KrCl Excimer Lamps: The Impact of Optical Filtering(†)

人体皮肤模型暴露于氯化氪准分子灯:光学滤波的影响(†)

Buonanno, Manuela; Welch, David; Brenner, David J