David C Hay相关文献与解析，生知库 | 链接生命科学的每一步

Single-cell morphological tracking of cell states to identify small-molecule modulators of liver differentiation

单细胞形态追踪细胞状态以识别肝脏分化的小分子调节剂

doi:10.1016/j.isci.2025.111871

Rebecca E Graham, Runshi Zheng, Jesko Wagner, Asier Unciti-Broceta, David C Hay, Stuart J Forbes, Victoria L Gadd, Neil O Carragher

Chemically programmed metabolism drives a superior cell fitness for cartilage regeneration

化学程序化代谢促进细胞适应软骨再生

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.adp4408

Yishan Chen, Yiyang Yan, Ruonan Tian, Zixuan Sheng, Liming Li, Jiachen Chen, Yuan Liao, Ya Wen, Junting Lu, Xinyu Liu, Wei Sun, Haoyu Wu, Youguo Liao, Xianzhu Zhang, Xuri Chen, Chengrui An, Kun Zhao, Wanlu Liu, Jianqing Gao, David C Hay, Hongwei Ouyang

Screening a Compound Library to Identify Additives That Boost Cytochrome P450 Enzyme Function in Vascularised Liver Spheres

筛选化合物库以识别可增强血管化肝球中细胞色素 P450 酶功能的添加剂

期刊:Cells

影响因子:5.1

doi:10.3390/cells13181594

Baltasar Lucendo-Villarin, Yu Wang, Sunil K Mallanna, Erin A Kimbrel, David C Hay

Early interferon lambda production is induced by double-stranded RNA in iPS-derived hepatocyte-like cells

双链 RNA 诱导 iPS 衍生的肝细胞样细胞产生早期干扰素 λ

期刊:Oxford Open Immunology

影响因子:

doi:10.1093/oxfimm/iqae004

Vasile Mihai Sularea, Ruchi Sharma, David C Hay, Cliona O'Farrelly

In Vivo Tumorigenicity of the 20q11.21 Amplicon in an Engraftment Model of hPSCs and Differentiated Liver Cells

20q11.21 扩增子在 hPSC 和分化肝细胞植入模型中的体内致瘤性

期刊:Journal of Stem Cells & Regenerative Medicine

影响因子:1.1

doi:10.46582/jsrm.1901002

Chris S Pridgeon, Shiva Seyed Forootan, Fang Zhang, Nicholas Harper, Daniel Palmer, Richard Weightmann, Sian Gregory, Zoe Hewitt, Duncan Baker, Jason Halliwell, Harry Moore, Emanuele Ricci, Peter W Andrews, Harish Poptani, David C Hay, B Kevin Park, Chris E P Goldring

Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease

从废弃供体肝脏中提取的人类胆管上皮细胞可在胆道疾病小鼠模型中恢复胆管结构和功能。

期刊:Cell Stem Cell

影响因子:19.8

doi:10.1016/j.stem.2022.02.006

John M Hallett ，Sofia Ferreira-Gonzalez ，Tak Yung Man ，Alastair M Kilpatrick ，Hannah Esser ，Kayleigh Thirlwell ，Mark T Macmillan ，Daniel Rodrigo-Torres ，Benjamin J Dwyer ，Victoria L Gadd ，Candice Ashmore-Harris ，Wei-Yu Lu ，John P Thomson ，Maurits A Jansen ，Eoghan O'Duibhir ，Philip J Starkey Lewis ，Lara Campana ，Rhona E Aird ，Thomas S R Bate ，Alasdair R Fraser ，John D M Campbell ，Gabriel C Oniscu ，David C Hay ，Anthony Callanan ，Stuart J Forbes

Pluripotent Stem Cell-Derived Hepatocytes Inhibit T Cell Proliferation In Vitro through Tryptophan Starvation

多能干细胞衍生的肝细胞通过色氨酸饥饿抑制体外 T 细胞增殖

期刊:Cells

影响因子:5.1

doi:10.3390/cells11010024

Marco Romano, Raul Elgueta, Daniel McCluskey, Ana Maria Ortega-Prieto, Emilie Stolarczyk, Francesco Dazzi, Baltasar Lucendo-Villarin, Jose Meseguer-Ripolles, James Williams, Giorgia Fanelli, David C Hay, Fiona M Watt, Giovanna Lombardi

Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure

富马酸二甲酯可减少对乙酰氨基酚暴露后的肝细胞衰老

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2021.102552

Jose Meseguer-Ripolles ,Baltasar Lucendo-Villarin ,Carl Tucker ,Sofia Ferreira-Gonzalez ,Natalie Homer ,Yu Wang ,Philip J Starkey Lewis ,Enrique M Toledo ,Esther Mellado-Gomez ,Joanna Simpson ,Oliver Flint ,Himjyot Jaiswal ,Nicola L Beer ,Allan E Karlsen ,Stuart J Forbes ,James W Dear ,Jeremy Hughes ,David C Hay

Mathematical modelling of oxygen gradients in stem cell-derived liver tissue

干细胞来源的肝组织中氧梯度的数学建模

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0244070

Joseph A Leedale, Baltasar Lucendo-Villarin, Jose Meseguer-Ripolles, Alvile Kasarinaite, Steven D Webb, David C Hay

Ultrafast crosslinking, strongly adhesive de novo protein hydrogels promote cartilage regeneration

超快交联、强粘附性的新生蛋白水凝胶促进软骨再生

Single-cell morphological tracking of cell states to identify small-molecule modulators of liver differentiation

单细胞形态追踪细胞状态以识别肝脏分化的小分子调节剂

Chemically programmed metabolism drives a superior cell fitness for cartilage regeneration

化学程序化代谢促进细胞适应软骨再生

Screening a Compound Library to Identify Additives That Boost Cytochrome P450 Enzyme Function in Vascularised Liver Spheres

筛选化合物库以识别可增强血管化肝球中细胞色素 P450 酶功能的添加剂

Early interferon lambda production is induced by double-stranded RNA in iPS-derived hepatocyte-like cells

双链 RNA 诱导 iPS 衍生的肝细胞样细胞产生早期干扰素 λ

In Vivo Tumorigenicity of the 20q11.21 Amplicon in an Engraftment Model of hPSCs and Differentiated Liver Cells

20q11.21 扩增子在 hPSC 和分化肝细胞植入模型中的体内致瘤性

Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease

从废弃供体肝脏中提取的人类胆管上皮细胞可在胆道疾病小鼠模型中恢复胆管结构和功能。

Pluripotent Stem Cell-Derived Hepatocytes Inhibit T Cell Proliferation In Vitro through Tryptophan Starvation

多能干细胞衍生的肝细胞通过色氨酸饥饿抑制体外 T 细胞增殖

Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure

富马酸二甲酯可减少对乙酰氨基酚暴露后的肝细胞衰老

Mathematical modelling of oxygen gradients in stem cell-derived liver tissue

干细胞来源的肝组织中氧梯度的数学建模