日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Smad4 restricts injury-provoked biliary proliferation and carcinogenesis

Smad4抑制损伤诱发的胆管增生和癌变

William B Alexander ,Wenjia Wang ,Margaret A Hill ,Michael R O'Dell ,Luis I Ruffolo ,Bing Guo ,Katherine M Jackson ,Nicholas Ullman ,Scott C Friedland ,Matthew N McCall ,Ankit Patel ,Nathania Figueroa-Guilliani ,Mary Georger ,Brian A Belt ,Christa L Whitney-Miller ,David C Linehan ,Patrick J Murphy ,Aram F Hezel

Platelet-activating factor (PAF) promotes immunosuppressive neutrophil differentiation within tumors

血小板活化因子 (PAF) 促进肿瘤内免疫抑制中性粒细胞分化

Ankit Dahal, Yeonsun Hong, Jocelyn S Mathew, Adam Geber, Sarah Eckl, Stephanie Renner, Cooper J Sailer, Allison T Ryan, Sana Mir, Kihong Lim, David C Linehan, Scott A Gerber, Minsoo Kim

CD73 and PD-L1 dual blockade amplifies antitumor efficacy of SBRT in murine PDAC models

CD73 和 PD-L1 双重阻断增强了小鼠 PDAC 模型中 SBRT 的抗肿瘤功效

Jian Ye, Nicholas W Gavras, David C Keeley, Angela L Hughson, Gary Hannon, Tara G Vrooman, Maggie L Lesch, Carl J Johnston, Edith M Lord, Brian A Belt, David C Linehan, Jim Eyles, Scott A Gerber

Toll-like receptor 7/8 agonist R848 alters the immune tumor microenvironment and enhances SBRT-induced antitumor efficacy in murine models of pancreatic cancer

Toll 样受体 7/8 激动剂 R848 改变免疫肿瘤微环境并增强小鼠胰腺癌模型中 SBRT 诱导的抗肿瘤功效

Jian Ye, Bradley N Mills, Shuyang S Qin, Jesse Garrett-Larsen, Joseph D Murphy, Taylor P Uccello, Booyeon J Han, Tara G Vrooman, Carl J Johnston, Edith M Lord, Brian A Belt, David C Linehan, Scott A Gerber

Modulation of the Human Pancreatic Ductal Adenocarcinoma Immune Microenvironment by Stereotactic Body Radiotherapy

立体定向放射治疗对人类胰腺导管腺癌免疫微环境的调节

Bradley N Mills, Haoming Qiu, Michael G Drage, Chunmo Chen, Jocelyn S Mathew, Jesse Garrett-Larsen, Jian Ye, Taylor P Uccello, Joseph D Murphy, Brian A Belt, Edith M Lord, Alan W Katz, David C Linehan, Scott A Gerber

Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo

鉴定出一种维生素D受体拮抗剂MeTC7,它能抑制体内异种移植瘤和转基因肿瘤的生长

Negar Khazan ,Kyu Kwang Kim ,Jeanne N Hansen ,Niloy A Singh ,Taylor Moore ,Cameron W A Snyder ,Ravina Pandita ,Myla Strawderman ,Michiko Fujihara ,Yuta Takamura ,Ye Jian ,Nicholas Battaglia ,Naohiro Yano ,Yuki Teramoto ,Leggy A Arnold ,Russell Hopson ,Keshav Kishor ,Sneha Nayak ,Debasmita Ojha ,Ashoke Sharon ,John M Ashton ,Jian Wang ,Michael T Milano ,Hiroshi Miyamoto ,David C Linehan ,Scott A Gerber ,Nada Kawar ,Ajay P Singh ,Erdem D Tabdanov ,Nikolay V Dokholyan ,Hiroki Kakuta ,Peter W Jurutka ,Nina F Schor ,Rachael B Rowswell-Turner ,Rakesh K Singh ,Richard G Moore

HE4 Overexpression by Ovarian Cancer Promotes a Suppressive Tumor Immune Microenvironment and Enhanced Tumor and Macrophage PD-L1 Expression

卵巢癌中 HE4 的过度表达促进了抑制性肿瘤免疫微环境并增强了肿瘤和巨噬细胞 PD-L1 的表达

Rachael B Rowswell-Turner, Rakesh K Singh, Anze Urh, Naohiro Yano, Kyu Kwang Kim, Negar Khazan, Ravina Pandita, Umayal Sivagnanalingam, Virginia Hovanesian, Nicole E James, Jennifer R Ribeiro, Sindhuja Kadambi, David C Linehan, Richard G Moore

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

肿瘤间遗传异质性在新型小鼠同步黑色素瘤模型中产生独特的肿瘤微环境

Shuyang S Qin, Booyeon J Han, Alyssa Williams, Katherine M Jackson, Rachel Jewell, Alexander C Chacon, Edith M Lord, David C Linehan, Minsoo Kim, Alexandre Reuben, Scott A Gerber, Peter A Prieto

Assessing the Magnitude of Immunogenic Cell Death Following Chemotherapy and Irradiation Reveals a New Strategy to Treat Pancreatic Cancer

评估化疗和放疗后免疫原性细胞死亡的程度揭示了治疗胰腺癌的新策略

Jian Ye, Bradley N Mills, Tony Zhao, Booyeon J Han, Joseph D Murphy, Ankit P Patel, Carl J Johnston, Edith M Lord, Brian A Belt, David C Linehan, Scott A Gerber

Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment

立体定向放射治疗联合白细胞介素-12疗法通过重塑免疫微环境根除胰腺肿瘤

Bradley N Mills ,Kelli A Connolly ,Jian Ye ,Joseph D Murphy ,Taylor P Uccello ,Booyeon J Han ,Tony Zhao ,Michael G Drage ,Aditi Murthy ,Haoming Qiu ,Ankit Patel ,Nathania M Figueroa ,Carl J Johnston ,Peter A Prieto ,Nejat K Egilmez ,Brian A Belt ,Edith M Lord ,David C Linehan ,Scott A Gerber