Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans
遗传的C端TREX1变异会破坏同源重组修复，从而导致果蝇、小鼠和人类出现衰老和DNA损伤表型。
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-49066-7
Samuel D Chauvin # ,Shoichiro Ando # ,Joe A Holley # ,Atsushi Sugie ,Fang R Zhao ,Subhajit Poddar ,Rei Kato ,Cathrine A Miner ,Yohei Nitta ,Siddharth R Krishnamurthy ,Rie Saito ,Yue Ning ,Yuya Hatano ,Sho Kitahara ,Shin Koide ,W Alexander Stinson ,Jiayuan Fu ,Nehalee Surve ,Lindsay Kumble ,Wei Qian ,Oleksiy Polishchuk ,Prabhakar S Andhey ,Cindy Chiang ,Guanqun Liu ,Ludovic Colombeau ,Raphaël Rodriguez ,Nicolas Manel ,Akiyoshi Kakita ,Maxim N Artyomov ,David C Schultz ,P Toby Coates ,Elisha D O Roberson ,Yasmine Belkaid ,Roger A Greenberg ,Sara Cherry ,Michaela U Gack ,Tristan Hardy ,Osamu Onodera ,Taisuke Kato ,Jonathan J Miner
