日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gene therapy for cross-correction of somatic organs and the CNS in mucopolysaccharidosis II in rodents and non-human primates

啮齿类和非人类灵长类粘多糖贮积症 II 的躯体器官和中枢神经系统交叉矫正的基因治疗

Nancy Chen, David E Ehmann, Robert Crooker, Katayoun Derakhchan, Xiaodong Fang, Brian Felice, Elizabeth J Galbreath, Charles Glaus, Hongbo Gu, Yan Huang, Christine Li, Xing Li, Nan Liu, Kathleen Palmieri, Damir Simic, Joseph Sypek, Susan Thompson, Christopher T Winkelmann, Vivian W Choi

Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

通过工程化的卵泡抑素阻断肌生长抑制素和促活素可导致肥大,并且比单独阻断肌生长抑制素更有效改善 mdx 小鼠的营养不良病理

Andrea Iskenderian, Nan Liu, Qingwei Deng, Yan Huang, Chuan Shen, Kathleen Palmieri, Robert Crooker, Dianna Lundberg, Niksa Kastrapeli, Brian Pescatore, Alla Romashko, John Dumas, Robert Comeau, Angela Norton, Jing Pan, Haojing Rong, Katayoun Derakhchan, David E Ehmann

Translating slow-binding inhibition kinetics into cellular and in vivo effects

将缓慢结合抑制动力学转化为细胞和体内效应

Grant K Walkup, Zhiping You, Philip L Ross, Eleanor K H Allen, Fereidoon Daryaee, Michael R Hale, John O'Donnell, David E Ehmann, Virna J A Schuck, Ed T Buurman, Allison L Choy, Laurel Hajec, Kerry Murphy-Benenato, Valerie Marone, Sara A Patey, Lena A Grosser, Michele Johnstone, Stephen G Walker, Pe