日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hyaluronan in mesenchymal stromal cell lineage differentiation from human pluripotent stem cells: application in serum free culture

透明质酸在人类多能干细胞间充质基质细胞谱系分化中的作用:在无血清培养中的应用

Paul A De Sousa, Leo Perfect, Jinpei Ye, Kay Samuels, Ewa Piotrowska, Martin Gordon, Ryan Mate, Elsa Abranches, Thomas M Wishart, David H Dockrell, Aidan Courtney0

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

缺氧会影响肺损伤中的免疫环境,并促进炎症持续存在。

Ananda S Mirchandani ,Stephen J Jenkins # ,Calum C Bain # ,Manuel A Sanchez-Garcia ,Hannah Lawson ,Patricia Coelho ,Fiona Murphy ,David M Griffith ,Ailiang Zhang ,Tyler Morrison ,Tony Ly ,Simone Arienti ,Pranvera Sadiku ,Emily R Watts ,Rebecca S Dickinson ,Leila Reyes ,George Cooper ,Sarah Clark ,David Lewis ,Van Kelly ,Christos Spanos ,Kathryn M Musgrave ,Liam Delaney ,Isla Harper ,Jonathan Scott ,Nicholas J Parkinson ,Anthony J Rostron ,J Kenneth Baillie ,Sara Clohisey ,Clare Pridans ,Lara Campana ,Philip Starkey Lewis ,A John Simpson ,David H Dockrell ,Jürgen Schwarze ,Nikhil Hirani ,Peter J Ratcliffe ,Christopher W Pugh ,Kamil Kranc ,Stuart J Forbes ,Moira K B Whyte ,Sarah R Walmsley

Neutrophil HIF-1α stabilization is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle

通过甘油 3-磷酸穿梭产生的线粒体 ROS 增强了中性粒细胞 HIF-1α 的稳定性

Joseph A Willson, Simone Arienti, Pranvera Sadiku, Leila Reyes, Patricia Coelho, Tyler Morrison, Giulia Rinaldi, David H Dockrell, Moira K B Whyte, Sarah R Walmsley

Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis

中性粒细胞通过糖异生和糖原生成为有效的免疫反应提供能量。

Pranvera Sadiku ,Joseph A Willson ,Eilise M Ryan ,David Sammut ,Patricia Coelho ,Emily R Watts ,Robert Grecian ,Jason M Young ,Martin Bewley ,Simone Arienti ,Ananda S Mirchandani ,Manuel A Sanchez Garcia ,Tyler Morrison ,Ailing Zhang ,Leila Reyes ,Tobias Griessler ,Privjyot Jheeta ,Gordon G Paterson ,Christopher J Graham ,John P Thomson ,Kenneth Baillie ,A A Roger Thompson ,Jessie-May Morgan ,Abel Acosta-Sanchez ,Veronica M Dardé ,Jordi Duran ,Joan J Guinovart ,Gio Rodriguez-Blanco ,Alex Von Kriegsheim ,Richard R Meehan ,Massimiliano Mazzone ,David H Dockrell ,Bart Ghesquiere ,Peter Carmeliet ,Moira K B Whyte ,Sarah R Walmsley

Pneumolysin Is Responsible for Differential Gene Expression and Modifications in the Epigenetic Landscape of Primary Monocyte Derived Macrophages

肺炎球菌溶血素负责原代单核细胞衍生巨噬细胞表观遗传景观中的差异基因表达和修饰

Joby Cole, Adrienn Angyal, Richard D Emes, Tim John Mitchell, Mark J Dickman, David H Dockrell

The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia

时钟基因 Bmal1 抑制巨噬细胞运动、吞噬作用,并削弱对肺炎的防御能力

Gareth B Kitchen, Peter S Cunningham, Toryn M Poolman, Mudassar Iqbal, Robert Maidstone, Matthew Baxter, James Bagnall, Nicola Begley, Ben Saer, Tracy Hussell, Laura C Matthews, David H Dockrell, Hannah J Durrington, Julie E Gibbs, John F Blaikley, Andrew S Loudon, David W Ray

Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease

Pellino-1 调节炎症性肺病模型中对流感嗜血杆菌的免疫反应

Bethany M Hughes, Charlotte S Burton, Abigail Reese, Maisha F Jabeen, Carl Wright, Jessica Willis, Nika Khoshaein, Elizabeth K Marsh, Peter Peachell, Shao C Sun, David H Dockrell, Helen M Marriott, Ian Sabroe, Alison M Condliffe, Lynne R Prince

Human skin commensals augment Staphylococcus aureus pathogenesis

人类皮肤共生菌增强金黄色葡萄球菌的致病作用

Emma Boldock, Bas G J Surewaard, Daria Shamarina, Manli Na, Ying Fei, Abukar Ali, Alexander Williams, Eric J G Pollitt, Piotr Szkuta, Paul Morris, Tomasz K Prajsnar, Kathy D McCoy, Tao Jin, David H Dockrell, Jos A G van Strijp, Paul Kubes, Stephen A Renshaw, Simon J Foster

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

脯氨酰羟化酶 2 失活可增强糖原储存并促进过度中性粒细胞反应

Pranvera Sadiku, Joseph A Willson, Rebecca S Dickinson, Fiona Murphy, Alison J Harris, Amy Lewis, David Sammut, Ananda S Mirchandani, Eilise Ryan, Emily R Watts, A A Roger Thompson, Helen M Marriott, David H Dockrell, Cormac T Taylor, Martin Schneider, Patrick H Maxwell, Edwin R Chilvers, Massimilli

Analysis of histone post translational modifications in primary monocyte derived macrophages using reverse phase×reverse phase chromatography in conjunction with porous graphitic carbon stationary phase

使用反相×反相色谱结合多孔石墨碳固定相分析原代单核细胞衍生的巨噬细胞中的组蛋白翻译后修饰

Thomas C Minshull, Joby Cole, David H Dockrell, Robert C Read, Mark J Dickman